An herbal cream reduces erythema of sensitive skin

Zhang, Yuanjin; Yuan, Jing; Humbert, Philippe; Fan, Xiaoqing; Cha, Yusi; Guo, Yanni

doi:10.1111/jocd.13610

Cited by 10 publications

(10 citation statements)

References 27 publications

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“… 78 In addition, two articles involved multiple products, and lower TEWL values, higher SCH values, and lower EI values were observed relative to the placebo. 72 , 82 Two articles that included multiproduct comparisons noticed no significant changes in the TEWL values with respect to the baseline. 74 , 81 …”

Section: Resultsmentioning

confidence: 99%

“… 70–74 Three out of the five articles applied lactic acid to the nasolabial folds, 70 , 71 , 73 one applied sodium lauryl sulfate to the forearm, 74 and another applied lactic acid to the cheek. 72 In addition to the classical LAST, dermatologists’ diagnostics and questionnaires were also used. Four studies asked dermatologists to differentiate sensitive skin groups, 75–77 while five studies involved screening using self-assessments.…”

Section: Resultsmentioning

confidence: 99%

“…For both products and raw materials, their efficacies were mainly assessed in terms of their ability to moisturize, produce anti-allergy and anti-inflammatory reactions, reduce erythema, and enhance or repair barrier function. The selection of biophysical parameters was also slightly different depending on the product, but according to the frequency of use, the following data were obtained: 89.47% were assessed with TEWL (n=17), 55 , 70–74 , 76–82 , 84–87 63.16% with SCH (n=12), 70–74 , 76 , 78 , 79 , 82–84 , 87 31.58% with the EI (n=6), 70 , 72 , 74 , 76 , 81 , 82 15.79% with the a* value (n=3), 72 , 82 , 87 10.53% with sebum content (n=2), 70 , 77 10.53% with skin temperature (n=2), 79 , 85 10.53% with pH (n=2), 76 , 79 10.53% with blood flow (n=2), 80 , 87 10.53% with VISIA (n=2), 72 , 75 5.26% with skin elasticity (n=1), 76 and 5.26% with the L* value (n=1). 72 …”

Section: Resultsmentioning

confidence: 99%

“… 70 , 71 , 75 , 76 , 78 , 82–84 , 87 All articles involving EI values showed decreases after treatment (topical agents, herbal cream). 70 , 72–74 , 76 , 82 One randomized controlled trial in sensitive skin subjects using moisturizer showed no significant changes in the TEWL value after treatment compared to placebo without active ingredients. 78 In addition, two articles involved multiple products, and lower TEWL values, higher SCH values, and lower EI values were observed relative to the placebo.…”

Section: Resultsmentioning

confidence: 99%

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The Challenges in Investigating the Pathogenesis of Sensitive Skin by Noninvasive Measurements: A Systematic Review

Yan

Zhao

Han

et al. 2023

CCID

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Sensitive skin (SS) is a common cutaneous condition that seriously affects people’s quality of life, but studies of sensitive skin pathogenesis are unclear, the exploration are ongoing, and the biophysical properties of sensitive skin disagree with the study results. In this paper, we summarize the noninvasive biophysical and imaging instrumental methods used for sensitive skin and provide support for the classification of sensitive skin subtypes to prescribe precise treatment. PubMed and Web of Science databases were searched according to PRISMA guidelines for articles from January 1971 to May 2022 that used noninvasive biophysical or imaging methods to monitor adult subjects with sensitive skin. The quality of the included articles was determined based on 22 items of the STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) statement. A total of 55 studies were included, representing 8 biophysical and 5 imaging methods and their applications in treatment efficacy evaluation studies. The biophysical parameter and cutaneous morphological property changes in sensitive skin subjects were observed. The quality of the studies was relatively low, and there was high variability in results between studies. Several parameters have shown tremendous potential in exploring the pathogenesis with different sensitive skin subtypes: type I may be detected with higher transepidermal water loss and lower stratum corneum hydration values, as well as with thinner epidermis with a shallower and more irregular honeycomb structure; Type II and III are more prone to higher blood flow, lower current perception threshold than normal skin. This systematic review identifies key reasons for the lack of uniform trends in noninvasive measurements and recommends the use of effective selection instruments or relevant parameters to explore the pathogenesis of sensitive skin, and to differentiate the subtypes of sensitive skin for achieving the precise treatment.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

The Challenges in Investigating the Pathogenesis of Sensitive Skin by Noninvasive Measurements: A Systematic Review

Yan

Zhao

Han

et al. 2023

CCID

View full text Add to dashboard Cite

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“…Clinically, the evaluation of the above-mentioned symptoms or signs, and the determination of objective laboratory parameters could be used to assess the applicability of a certain cosmetics for SS. In the recent years, cosmetics developed for SS are mainly aimed at repairing the barrier function of skin, alleviating skin sensitivity and inflammatory response, [ 4 , 5 ] so as to enhance skin tolerance. In the presented paper, the variation of the following items in different periods, namely, self-feeling report, the transepidermal water loss rate (TEWL), stratum corneum (SC) hydration, melanin index (MI), erythema index (EI), dendritic cells, infiltration of inflammatory cells and lactic acid tingling test (LAST) were investigated and compared.…”

Section: Introductionmentioning

confidence: 99%

Study on screening and evaluation methods of cosmetics for people with facial sensitive skin

Lyu¹,

Quan-ping²,

Wang³

et al. 2022

Medicine

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The purpose of this study is to screen and evaluate cosmetic products for sensitive skin on the face.Methods: Thirty-five subjects with positive lactic acid sting test (LAST) were recruited from the staff of our hospital from November 2019 to February 2020. First, the human skin enclosed patch test of cosmetic gel (abbreviated as gel) was performed, and then the tested products were continuously applied for 4 weeks to complete the long-term efficacy test. Subjects' sensation of application, pruritus, tingling and burning were assessed on a 0 to 9 scale prior to, 14, and 28 days after topical application. Moreover, the transepidermal water loss rate (TEWL), stratum corneum (SC) hydration, melanin index (MI), erythema index (EI) and dendritic cells and inflammatory cell infiltration were noninvasively detected by the tester. LAST were performed before applying, 14 and 28 days after application, and then the test results were compared.Results: In this study, a total of 34 people participated in the test. The results of human skin enclosed patch test indicated that only 1 case of grade 1 reaction occurred among the tested subjects. The subjects felt good after applying the products, and the gel showed high degree of skin comfortable, no irritation and good tolerability. Subjective safety evaluation illustrated that the scores of pruritus, tingling and burning of the subjects decreased in D14 and D28 patient revisit, showing statistically significant differences (P < .05). When the gel was applied for 4 weeks, TEWL (8.42 ± 1.12) and EI (201.35 ± 13.51) were lower than the results before application (P < .05), and the SC hydration (65.36 ± 2.56) was higher than that before application (P < .05). There was no correlation between the SC hydration and TEWL (R = 0.092, P = .416). The results of skin CT indicated that the number of facial dendritic cells decreased in 17 subjects (accounting for 50%) in D28 patient revisit, and the degree of inflammatory cell infiltration decreased in 27 subjects (accounting for 80%). Compared with the baseline value, the LAST score and total sensory score decreased after application the product for 4 weeks, and the difference was statistically significant (the mean value of P < .05). Conclusion:The subjective feeling of application and efficacy of cosmetics in people with sensitive skin could be successfully evaluated by the comprehensive application of human skin enclosed patch test, long-term trial test, subjective safety evaluation and objective efficacy evaluation. And it provides the basis to judge whether the cosmetic is consistent with the efficacy claim of sensitive skin.

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Clinical study of a spray containing birch juice for repairing sensitive skin

Shu

Zhao²,

Huo

et al. 2023

Arch Dermatol Res

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Sensitive skin is described as an unpleasant sensory response to a stimulus that should not cause a sensation. Sensitive skin affects an increasing proportion of the population. Sixty-seven participants who tested positive to lactic acid sting test were recruited and randomized into two groups to observe the clinical efficacy and safety of a new birch juice spray for repairing sensitive skin. One group used test spray A, while the other group used spray B as a control. Both groups were sprayed six times daily for 28 days. Noninvasive testing instruments were used to measure stratum corneum hydration, sebum content, transepidermal water loss rates, skin blood perfusion and current perception threshold before and after using spray. Facial images were captured by VISIA-CR, and the image analysis program (Image‐Pro Plus) was used to analyze these to obtain the redness value of the facial skin. Moreover, lactic acid sting test scores and participants’ self-assessments were also performed at baseline, week 2 and week 4. Both sprays A and B significantly decreased the lactic acid sting test score, transepidermal water loss rates, skin blood perfusion, and redness, while increasing the stratum corneum hydration. Compared to spray B, spray A increased sensory nerve thresholds at 5 Hz and decreased the transepidermal water loss rates, skin blood perfusion, and lactic acid sting test score. Sprays containing birch juice improved cutaneous biophysical properties in participants with sensitive skin.

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An herbal cream reduces erythema of sensitive skin

Cited by 10 publications

References 27 publications

The Challenges in Investigating the Pathogenesis of Sensitive Skin by Noninvasive Measurements: A Systematic Review

The Challenges in Investigating the Pathogenesis of Sensitive Skin by Noninvasive Measurements: A Systematic Review

Study on screening and evaluation methods of cosmetics for people with facial sensitive skin

Clinical study of a spray containing birch juice for repairing sensitive skin

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