An HPTLC Method for the Evaluation of Two Medicinal Plants Commercially Available in the Indian Market Under the Common Trade Name Brahmadandi

Padashetty, S A; Mishra, S.H.

doi:10.1365/s10337-007-0318-3

Cited by 13 publications

(7 citation statements)

References 1 publication

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“…A well‐validated HPTLC protocol for lupeol quantification developed by Padashetty and Mishra () was followed but with slight modifications. A Camag TLC system equipped with a Camag Linomat V applicator and a Camag glass twin trough chamber (20 × 10 cm) were used for the analysis.…”

Section: Methodsmentioning

confidence: 99%

Design of Experiment Approach for the Process Optimisation of Microwave Assisted Extraction of Lupeol fromFicus racemosaLeaves Using Response Surface Methodology

Das

Mandal

2012

Phytochemical Analysis

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Section: Methodsmentioning

confidence: 99%

Design of Experiment Approach for the Process Optimisation of Microwave Assisted Extraction of Lupeol fromFicus racemosaLeaves Using Response Surface Methodology

Das

Mandal

2012

Phytochemical Analysis

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“…Gupta et al reported a 100% reduction on fertility of albino rats after the application of lupeol acetate. Likewise, traditional healers of Chhattisgarh in India use an extract from Echinops echinatus for the treatment of sexual disorders, also a paste prepared by mixing the root bark powder with the juice of Datura stramonium and Blumea lacera leaves is used to avoid premature ejaculation . Additionally, male rats treated with Echinops echinatus extracts, which contain high concentration of lupeol, reduced the level of testosterone and the testicular weight .…”

Section: Resultsmentioning

confidence: 98%

In Silico Prediction of the Toxic Potential of Lupeol

Ruiz-Rodríguez

Vedani

Flores-Mireles

et al. 2017

Chem. Res. Toxicol.

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Lupeol is a natural triterpenoid found in many plant species such as mango. This compound is the principal active component of many traditional herbal medicines. In the past decade, a considerable number of publications dealt with lupeol and its analogues due to the interest in their pharmacological activities against cancer, inflammation, arthritis, diabetes, and heart disease. To identify further potential applications of lupeol and its analogues, it is necessary to investigate their mechanisms of action, particularly their interaction with off-target proteins that may trigger adverse effects or toxicity. In this study, we simulated and quantified the interaction of lupeol and 11 of its analogues toward a series of 16 proteins known or suspected to trigger adverse effects employing the VirtualToxLab. This software provides a thermodynamic estimate of the binding affinity, and the results were challenged by molecular-dynamics simulations, which allow probing the kinetic stability of the underlying protein-ligand complexes. Our results indicate that there is a moderate toxic potential for lupeol and some of its analogues, by targeting and binding to nuclear receptors involved in fertility, which could trigger undesired adverse effects.

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“…The outcome shows that the methanolic concentrate of flying pieces of Tricholepis glaberrima which contains compound constituents like alkaloids (ephedrine), flavonoids, and go about as reversible monoamine oxidase inhibitors. Thus, that improves the exercises of dopamine and serotonin in the mind by hindering the enzymatic breakdown of the cerebrum synthetic substances by monoamine oxidase hindrance and has stimulant like action (Padashetty and Mishra, 2008;Padashetty and Shrihari, 2007). Additionally, the pathophysiology incorporates the vehicle of both dopamine and serotonin antecedents into the cerebrum by expanding the porousness of the blood-mind hindrance to the forerunners and evoking the energizer potential.…”

Section: Pharmacological Propertymentioning

confidence: 99%

The versatility of Tricholepis glaberrima (Brahmadandi): An Overview

Khare

ghosh

Sharma

et al. 2020

ECJ

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Since ancient times, crude drugs have been used as medicines and are of great importance for human beings. However, traditional knowledge about the use of medicinal plants is eroding day by day, and there was a need to document the everyday experience of these indigenous medicinal plants. Ayurveda describes the medicinal values and uses of plants for healthcare. By the course of time, various new plants got added to Ayurvedic material medica, Dravyaguna Vigyan. Tricholepis glaberrima (Brahmadandi) is one of them. This plant has great importance due to its nutritive value and a significant source of medicines as they have been found throughout human history.This plant is mostly used for its aphrodisiac property, but several unknown activities need to be taken seriously. This mini-review paper encompasses the Ayurvedic aspects as well as the phytochemistry structure and pharmacological activities of the Brahmadandi plant. The current review focuses on the updated information from various scientific studies and reports available in the context of the phytoconstituents and pharmacology of this plant. This review also provides adequate information about the use of this plant in an Indian system of medicine, Ayurveda.

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An HPTLC Method for the Evaluation of Two Medicinal Plants Commercially Available in the Indian Market Under the Common Trade Name Brahmadandi

Cited by 13 publications

References 1 publication

Design of Experiment Approach for the Process Optimisation of Microwave Assisted Extraction of Lupeol fromFicus racemosaLeaves Using Response Surface Methodology

Design of Experiment Approach for the Process Optimisation of Microwave Assisted Extraction of Lupeol fromFicus racemosaLeaves Using Response Surface Methodology

In Silico Prediction of the Toxic Potential of Lupeol

The versatility of Tricholepis glaberrima (Brahmadandi): An Overview

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