An Image Processing Algorithm for Facile and Reproducible Quantification of Vomocytosis
Neeraj Senthil,
Noah Pacifici,
Melissa Cruz-Acuña
et al.
Abstract:Vomocytosis is a process that occurs when internalized
fungal pathogens
escape from phagocytes without compromising the viability of the pathogen
and the host cell. Manual quantification of time-lapse microscopy
videos is currently used as the standard to study pathogen behavior
and vomocytosis incidence. However, human-driven quantification of
vomocytosis (and the closely related phenomenon, exocytosis) is incredibly
burdensome, especially when a large volume of cells and interactions
needs to be analyzed. In… Show more
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