An imidazo[1,5-α]pyridine-derivated fluorescence sensor for rapid and selective detection of sulfite

Yuan, Qing; Chen, Lili; Zhu, Xiaohua; Yuan, Zeng-Hui; Duan, Yongtao; Yang, Yu‐Shun; Wang, Bao‐Zhong; Wang, Xiaoming; Zhu, Hai‐Liang

doi:10.1016/j.talanta.2020.121087

Cited by 24 publications

(9 citation statements)

References 53 publications

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“…The reported impy compounds display mono-electronic oxidation (generally reversible), characterized by half-wave potential E 1/2 of about 400 mV (versus ferrocene/ferrocenium reference, Fc/Fc + ), as previously reported for impy derivatives and corresponding complexes. [4,26,28,67,111] Many works have been reported concerning the application of different impy products as molecular sensors, [121] for example for the quantification of hydrogen sulphide [122,109,123] and hydrogen polysulphides, [124] sulphur dioxide, [125] hypochlorous acid, [126][127][128] and metal ions such as Cu 2 + , [129] Cd 2 + and Zn 2 + , [130] Hg 2 + . [11] Moreover, impy products have been successfully employed as ratiometric pH-Sensors based on a dual emission pathway [29,30] or as fluorescent pH probes in living cells.…”

Section: Optical Behaviours and Reported Applications Of Impy Derivat...mentioning

confidence: 99%

Luminescent Imidazo[1,5‐a]pyridine Scaffold: Synthetic Heterocyclization Strategies‐Overview and Promising Applications

Volpi

2022

Asian J Org Chem

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In the last few years, imidazo[1,5‐a]pyridine derivatives have attracted growing attention due to their remarkable emissive behaviours, structural modification and biological properties. Previously published works emphasize the possible technological applications of this luminescent scaffold and demonstrate the stringent relationship between chemical substituents and optical properties. The main goal of this work is to provide a complete list of the reported achievements concerning these promising heterocyclization reactions obtained starting from a huge variety of reagents, catalysts, oxidants, dehydrating agents involved in various reaction conditions. Particular attention is focused on the final possible substitutions, conjugations and structural modifications of the reported synthetic approaches, a powerful aspect to design innovative and employable new luminescent imidazo[1,5‐a]pyridine products.

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Section: Optical Behaviours and Reported Applications Of Impy Derivat...mentioning

confidence: 99%

Luminescent Imidazo[1,5‐a]pyridine Scaffold: Synthetic Heterocyclization Strategies‐Overview and Promising Applications

Volpi

2022

Asian J Org Chem

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“…7 Therefore, it is necessary to develop an analytical method for the selective and sensitive recognition of H 2 S in the food industry, 7,8 environmental monitoring [9][10][11] and living organisms. [12][13][14][15] Recent years have witnessed several methods including colorimetry, 16 electrochemical assay, 17 capillary electrophoresis, 18 chromatography, 19 etc. for H 2 S detection.…”

Section: Introductionmentioning

confidence: 99%

A benzophenoxazine-based NIR fluorescent probe for the detection of hydrogen sulfide and imaging in living cells

Yin

Wang

et al. 2022

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“…Probes with cellular region-targeting features are valuable for studying the functions and morphologies of specific organelles under fluorescent imaging. To achieve organelle-specific imaging, the probes usually feature charges or stimulus-responsive properties to intracellular species, such as reactive oxygen species, metal ions, , anions, , biological sulfides, , specific overexpression proteases , in cancerous cells, and cell microenvironments, including viscosity, polarity, pH, and so forth. , Within many developed organelle-specific probes, supramolecular probes have been attractive in recent years due to their flexible stimulus-responsive characteristics. , The assembly–disassembly processes of these supramolecular conjugates have also been applied for targeting drug delivery and theranostic studies . The mitochondrion is one of the crucial organelles in cells.…”

Section: Introductionmentioning

confidence: 99%

Fluorescent Imaging Probe Targeting Mitochondria Based on Supramolecular Host–Guest Assembly and Disassembly

et al. 2022

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Fluorescent dyes and probes play an indispensable role in bioimaging. The mitochondrion is one of the crucial organelles which takes charge of energy production and is the primary site of aerobic respiration in the cell. To illuminate mitochondria, a series of supramolecular fluorescent imaging probes were developed based on the host–guest assembly of 1,4-bis[2-(4-pyridyl)ethenyl]-benzene (BPEB) derivatives and cucurbituril[6] (CB[6]). These host–guest conjugates can be efficiently internalized into cells due to their water solubility and target mitochondria according to their positive charges. In response to the intracellular microenvironments, these conjugates start dynamic disassembly. The released BPEBs show a highly hydrophobic feature, which can crystallize to form fluorescent solids that illuminate the mitochondria. The intracellular disassembly of the host–guest probes was evidenced by fluorescence lifetime imaging in situ. These smart mitochondrion-targeting fluorescent imaging probes can be available to investigate the structures and functions of mitochondria, which are of great significance in the intracellular dynamic transformation of supramolecular assemblies.

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An imidazo[1,5-α]pyridine-derivated fluorescence sensor for rapid and selective detection of sulfite

Cited by 24 publications

References 53 publications

Luminescent Imidazo[1,5‐a]pyridine Scaffold: Synthetic Heterocyclization Strategies‐Overview and Promising Applications

Luminescent Imidazo[1,5‐a]pyridine Scaffold: Synthetic Heterocyclization Strategies‐Overview and Promising Applications

A benzophenoxazine-based NIR fluorescent probe for the detection of hydrogen sulfide and imaging in living cells

Fluorescent Imaging Probe Targeting Mitochondria Based on Supramolecular Host–Guest Assembly and Disassembly

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