This work is part of the ONERA-TsAGI cooperative project NOWNA (NextGen Over the Wing Nacelle Aircraft) which investigates the potential of fan noise shielding for a transonic transport aircraft by installing a UHBR engine over its wing. The studied configuration is a derivative of the NOVA (Next Generation Onera Versatile Aircraft) for which cruise aerodynamic performance and low speed acoustics are evaluated and compared to a reference configuration with under wing engines. The present activity is a continuation of previous work on the numerical investigation of the acoustic advantages of Over the Wing Nacelle (OWN) configurations using ONERA's in-house CAA solver sAbrinA_v0 (see Mincu et al., AIAA 2017-3504). Whereas early computations did not assume any mean flow, the present work takes into account a realistic mean flow computed with ONERA's CFD solver FastS, at a global Mach number of 0.25 corresponding to take-off/landing flight conditions, and with a simple flow-through condition for the nacelle. Both CFD and CAA solvers use the Immersed Boundary Method (IBM) to deal with the realistic aircraft and nacelle geometries, which greatly simplifies the meshing stage. Here, this OWN configuration is compared to a more classic UWN (Under the Wing Nacelle) configuration, in terms of far field noise directivity.