An immunohistochemical and ultrastructural study of syringocystadenoma papilliferum

Yamamoto, Osamu; Doi, Yoshiaki; Hamada, Tetsuo; Hisaoka, Masanori; Sasaguri, Yasuyuki

doi:10.1046/j.1365-2133.2002.05027.x

Cited by 59 publications

(58 citation statements)

References 39 publications

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“…55 Syringocystadenocarcinoma papilliferum (fig 8C,D) is very rare, and as characterised histologically by disorderly arrangement of papillary projections, cytological atypia and loss of doublelayered epithelium. 56 …”

Section: Scap and Syringocystadenocarcinoma Papilliferummentioning

confidence: 99%

Skin adnexal neoplasms—part 2: An approach to tumours of cutaneous sweat glands

2006

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Tumours of cutaneous sweat glands are uncommon, with a wide histological spectrum, complex classification and many different terms often used to describe the same tumour. Furthermore, many eccrine/apocrine lesions coexist within hamartomas or within lesions with composite/mixed differentiation. In addition to the eccrine and apocrine glands, two other skin sweat glands have recently been described: the apoeccrine and the mammary-like glands of the anogenital area. In this review (the second of two articles on skin adnexal neoplasms), common as well as important benign and malignant lesions of cutaneous sweat glands are described, and a summary for differentiating primary adnexal neoplasms from metastatic carcinoma is outlined, striving to maintain a common and acceptable terminology in this complex subject. Composite/mixed adnexal tumours are also discussed briefly.

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Section: Scap and Syringocystadenocarcinoma Papilliferummentioning

confidence: 99%

Skin adnexal neoplasms—part 2: An approach to tumours of cutaneous sweat glands

2006

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“…However a few may derive from eccrine sweat glands, so the histogenesis remains controversial. 28 Syringocystadenoma papilliferum is an exceedingly rare neoplasm often occurs in association with nevus sebaceous. Almost half are present at birth and or appear during infancy.…”

Section: Study On Skin Appendageal Tumorsmentioning

confidence: 99%

A clinico-histopathological study on skin appendageal tumors

et al. 2016

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Background: Skin Appendageal tumors are a large and diverse group of tumors that are commonly classiied according to their state of appendageal differentiation: follicular, sebaceous, eccrine and apocrine. Objectives of this study were to study the clinic-epidemiological proile of skin appendageal tumors and to correlate the clinico-histopathological diagnosis. Materials and Methods:This was a retrospective and prospective study which included all cases of skin adnexal tumours diagnosed histologically during the period of four and half years. Tumors were analyzed considering the anatomic location, duration, size and type of the tumour, along with age and sex of the patient. The Histological characterization was done according to the WHO classiication system and was correlated with the clinical diagnosis. Collected data were analysed using SPSS PC+ 11.5 Version for statistical analysis.Results: A total of 70 neoplasms of skin appendages included, 68 (97.1%) were benign and 2 (2.9%) was malignant. Female comprised of 47 (67.1%) and 23 (32.9%) were male. The mean age was 39.23 years. Of all, 43 (61.4%) tumors were follicular, 18 (25.7%) were eccrine, 7 (10%) were apocrine and 2 (2.9%) were with sebaceous differentiation. The three commonest tumors encountered in this study were Pilomatricoma (21.4%), Keratoacanthoma (17.1%) and Trichoepithelioma (14.3%). Clinically, 13/70 (18.5%) cases were diagnosed as SAT.

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“…Overall, the tubular cystic lesions had a similar CK expression to that in the secretory portion of sweat glands, as has been previously reported. 2 In conclusion, CK expression within the squamous epithelium associated with SCAP was similar to that of the infrainfundibulum. This is consistent with the results of a previous report, 7 and suggests that SCAP shows a broad, diversified heterogeneous spectrum of differentiation towards the infrainfundibulum and secretory portion of the sweat glands.…”

Section: Discussionmentioning

confidence: 74%

Keratinizing Squamous Epithelium Associated withSyringocystadenoma PapilliferumDifferentiates towards Infrainfundibulum: Case Report with Immunohistochemical Study of Cytokeratins

et al. 2005

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We describe a case of Syringocystadenoma papilliferum (SCAP) with keratinizing squamous epithelium in a 26-year-old female presenting with a dark brown to black nodule on her forehead. After surgical excision, the specimen was examined immunohistochemically using antibodies against cytokeratin (CK) 1, 8, 10, 14, 17, 18 and 19. Within the keratinizing squamous epithelium, CK1, 10, 14 and 17 were present, whereas the other CKs were absent. Based on CK expression, keratinizing squamous epithelium in SCAP seems to differentiate towards the infrainfundibulum.

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An immunohistochemical and ultrastructural study of syringocystadenoma papilliferum

Cited by 59 publications

References 39 publications

Skin adnexal neoplasms—part 2: An approach to tumours of cutaneous sweat glands

Skin adnexal neoplasms—part 2: An approach to tumours of cutaneous sweat glands

A clinico-histopathological study on skin appendageal tumors

Keratinizing Squamous Epithelium Associated withSyringocystadenoma PapilliferumDifferentiates towards Infrainfundibulum: Case Report with Immunohistochemical Study of Cytokeratins

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