An IMPLICATION-logic-based fluorescent probe for sequential detection of Cu²⁺ and phosphates in living cells

Abstract

The Cu2+ and inorganic phosphates play an extremely important role in the organism and the environment. However, designing simultaneous identification and detection of Cu2+ and phosphates probe to construct multi-input...

AIE -active TPA modified Schiff base for successive sensing of Cu2+ and His via an on–off–on method and its application in bioimaging

“…Simultaneously, the peaks at 295 nm and 423 nm were lowered by degrees; this was derived from the paramagnetic quenching effect of Cu 2+ . 21,33 Two isosbestic points at 320 nm and 391 nm demonstrated the formation of an HL -Cu complex. After adding 0.5 equiv.…”

“…Owing to the d 9 electron configuration of Cu 2+ , the excited electrons transferred to the unfilled d-orbital of Cu 2+ instead of returning to the ground state of the ligand in the resultant Cu( ii ) complex, thereby activating non-radiative processes (intersystem crossing). 20,21 However, the concentration of HL decreased with the coordination of Cu 2+ , and the amount of HL aggregates dwindled in the detection system, hence lowering emission intensity. With the further addition of 0.2–0.5 equiv.…”

“…processes (intersystem crossing). 20,21 However, the concentration of HL decreased with the coordination of Cu 2+ , and the amount of HL aggregates dwindled in the detection system, hence lowering emission intensity. With the further addition of 0.2-0.5 equiv.…”

“…This optical signal amplification effect makes them suitable for constructing “turn-off” fluorescence probes. Considering the paramagnetic quenching effect of Cu 2+ 20,21 and the large affinity of His with Cu 2+ , 13,22 we aim to develop an AIE-active fluorescence probe for the sequential identification of Cu 2+ and His.…”

Architecture of Easy-to-Synthesize and Superior Probe Based on Aminoquinoline Appended Naphthoquinone: Instant and On-Site Cu2+ Ion Quantification in Real Samples and Unusual Crystal Structure and Logic Gate Operations

“…There are a variety of colorimetric probe platforms, such as benzimidazole, , rhodamine, quinoline, , coumarin, anthraquinone, pyrene, triphenylamine, chromone, naphthalimide, calixarene, and Schiff base, for selective detection of Cu 2+ ions. However, many of them suffer from toilsome synthesis procedures, long response times, interferences from other ions, low matrix durability, narrow linear range, and lack of practical applications. ,,− …”