An improvement on water absorbing and permeating properties: Heparin immobilizing on acrylic acid‐grafted and collagen/chitosan‐immobilized wound dressing

Wang, Chyung‐Chyung; Chen, Cheng‐Chi; Chen, Frank-Len; Lin, Nien-Shih

doi:10.1002/app.28206

Cited by 6 publications

(1 citation statement)

References 32 publications

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“…Both were obtained from Sigma Co., Saint Louis, MO. The chemical structures for collagen and chitosan 17 are shown in Scheme 1. Other chemicals used were all reagent grade.…”

Section: Methodsmentioning

confidence: 99%

Antibacterial and swelling properties of N‐isopropyl acrylamide grafted and collagen/chitosan‐immobilized polypropylene nonwoven fabrics

Wang

Chen

2010

J Biomed Mater Res

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The different molar ratios of collagen/chitosan were used to be immobilized on polypropylene nonwoven fabrics grafted with N-isopropyl acrylamide (abbr. PP-g-NIPAAm-i-Col/Chi). For a controlled immobilizing time and NIPAAm concentration, the collagen/chitosan immobilized values and the antibacterial properties of PP-g-NIPAAm-i-Col/Chi increased with increasing amount of chitosan in the mixture of collagen/chitosan. The crosslinking reaction between the grafted polyNIPAAm and collagen/chitosan molecules was clearly confirmed by the examination of the spectra of the surface reflection infrared spectroscopy (IR). The values of water absorption and water diffusion coefficient of PP-g-NIPAAm-i-Col/Chi decreased with increase of the chitosan in the mixture of collagen/chitosan and the value of immobilized collagen/chitosan at the same pH value of buffering water. The PP-g-NIPAAm-i-Col/Chi have excellent water absorption, water permeability, and antibacterial properties and would be suitable for the healing of wounded skin area.

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“…Both were obtained from Sigma Co., Saint Louis, MO. The chemical structures for collagen and chitosan 17 are shown in Scheme 1. Other chemicals used were all reagent grade.…”

Section: Methodsmentioning

confidence: 99%