An in vitro analysis of the effect of adjunctive use of ozonated oil with a desensitizing agent on dentinal tubule occlusion

Veena, H.R.; Mathew, C. Afigith; Daniel, Riya Achamma; Shubha, Priya Babu; Sreeparvathy, R.; Pradhan, Neha

doi:10.1016/j.jobcr.2020.10.001

Cited by 11 publications

(13 citation statements)

References 18 publications

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“…This could be attributed to the obliterative action of glutaraldehyde, which enhances the desensitization properties of the ozonized sunflower oil. Supporting the efficacy of this oil, Veena H. R. et al [15] reported that it can contribute to the opening of dentinal tubules, providing an anti-inflammatory action in dental pulp [16]. Similar results to the present study, regarding the reduction of sensitivity when combining ozone with dental bleaching, were found by Al-Omiri et al3 (2018).…”

Section: Discussionsupporting

confidence: 91%

Efficacy of Ozonized Sunflower Oil with Tea Tree Oil as Desensitizing Agents in Dental Bleaching: Randomized and Double-Blind Clinical Trial

Schneider,

Cardoso,

Ueda

et al. 2023

JAMMR

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Background: Dental bleaching is one of the most commonly prescribed procedures in aesthetic dentistry due to its effectiveness and minimally invasive nature. However, a recurrent and challenging side effect is dentin hypersensitivity after the procedure. Aim: This study aimed to evaluate whether the use of ozonized oil combined with tea tree oil is effective in controlling post-bleaching dentin sensitivity. Methods: A randomized, double-blind, split-mouth clinical trial was conducted. Participants were divided into two experimental groups (n=29) according to the desensitization protocol: control group: potassium nitrate and sodium fluoride; test group: ozonized sunflower oil combined with tea tree oil. Both groups were applied before dental bleaching with 35% hydrogen peroxide. The obtained data were subjected to statistical analysis using a non-parametric Friedman repeated measures ANOVA test (p < 0.05), followed by the Durbin-Conover post hoc test (p < 0.05). Results: In the assessment of sensitivity level, there were no statistically significant differences between the test group and the control group. A higher level of sensitivity was observed for the lower arch after one hour of bleaching agent removal in both groups, and the color change was statistically equal between the two groups. Conclusion: The study concluded that the test group paste was as effective in reducing dental sensitivity caused by dental bleaching as the control group. Additionally, neither of the groups affected the bleaching capacity of hydrogen peroxide.

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Section: Discussionsupporting

confidence: 91%

Efficacy of Ozonized Sunflower Oil with Tea Tree Oil as Desensitizing Agents in Dental Bleaching: Randomized and Double-Blind Clinical Trial

Schneider,

Cardoso,

Ueda

et al. 2023

JAMMR

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“…Tubular obliteration was explained in the in vitro study conducted by Veena [20]. In this work, they found that the adjuvant application of ozonized oil with an obliterating desensitizing agent (Colgate Sensitive Pro-Relief containing 8% arginine, calcium carbonate, and 1450 ppm of fluoride as sodium monofluorophosphate) caused more compact deposition of particles in the mouth of the dentinal tubules compared to the application of the desensitizing agent isolated.…”

Section: Resultsmentioning

confidence: 88%

Ozonated Oil as a Desensitizing Protocol in External Dental Bleaching: A Clinical, Randomized and Double-Blind Study

Wiggers,

Mendonça,

Vanolli

et al. 2023

JAMMR

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Aims: This research aimed to evaluate the action of ozonized oil associated with an obliterating desensitizing agent in reducing post-dental bleaching sensitivity. Study Design: This was a randomized, prospective, double-blind, split-mouth study, in which the patient and evaluator were blinded to the distribution of the groups. Place and Duration of Study: The study was conducted at the Dentistry Clinics of the Local University from June to December 2021. Methodology: Forty patients were selected and divided into two groups according to the desensitizing agent used: control group (GC) - potassium nitrate and sodium fluoride and treatment group (GT) - sunflower oil ozonized and glutaraldehyde. In-office bleaching was performed with 35% hydrogen peroxide in a single clinical session. The following variables were evaluated: I – the intensity of sensitivity at different times in the same group; II – the intensity of sensitivity at different times in different groups; III- global sensitivity; IV - worse pain and V - color change, which was evaluated at the beginning of treatment and one week after the end of the treatment with the help of a VITA color scale. The risk analysis of tooth sensitivity of both groups was compared using McNemar's exact test. To analyze the intensity of tooth sensitivity, the Wilcoxon and Friedman tests were used, P < 0,05. Results: The study revealed that there were significant differences in the risk and degree of tooth sensitivity between the test and control groups. Out of the total participants, 14 did not experience sensitivity, while 66 did. The test group exhibited lower pain scores at 35 and 40 minutes compared to the control group. In the intragroup analysis, significant differences were found within both the test and control groups across multiple time intervals. The analysis of global sensitivity showed significant differences between the treatment approaches, with the group receiving the specific treatment demonstrating lower sensitivity values compared to the control group. However, there were no significant differences in the worst pain between the treatment approaches. Regarding bleaching effectiveness, there were no statistically significant differences between the test and control groups. The comparison did not show a significant variation in bleaching effectiveness. Conclusion: The protocol showed promising results as a less invasive and discomfort-free method. However, the study was limited to using only one bleaching agent, and further research with different bleaching agents could provide additional insights.

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“…With the results found, lower overall sensitivity was observed in the test group in which ozonized sun ower oil was initially applied and in sequence a desensitizing agent based on potassium nitrate with sodium uoride. Thus, it is suggested that the synergistic effect of ozone opening the mouth of the tubules followed by the denser deposition of the desensitizing agent inside these tubules provide a more e cient tubular occlusion and consequent decrease in trans sensitivity and after dental bleaching 19 .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the ozonated sunflower oil application on reducing sensitivity after at-home bleaching

Roque,

Mendonça,

Vanolli

et al. 2023

Preprint

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Objectives Due to controversial results in relation to the influence of desensitizing agents on sensitivity during bleaching, the present study evaluated the degree of tooth bleaching sensitivity, color change, and patient acceptability of desensitizing agents containing potassium nitrate/sodium fluoride (PNF) or ozonized sunflower oil associated with in-office bleaching with 35% hydrogen peroxide (HP). Materials and Methods A clinical trial was conducted with a split-mouth design. The sample consisted of 30 volunteers randomized into 2 experimental groups according to the desensitization protocol. Potassium nitrate and sodium fluoride was applied to the hemiarch corresponding to the control group for 10 minutes, while in the hemiarch of the test group, ozonized sunflower oil was applied for 2 minutes with a rubber cup in low rotation, followed by a potassium nitrate and sodium fluoride application for 10 minutes. In sequence, both arcades were bleached with 35% hydrogen peroxide for 50 minutes. Results Previous application of ozonated sunflower oil resulted in a significant reduction in sensitivity in the first 24 hours after removal of the bleaching gel, as well as the test group showed lower tooth sensitivity in times measured up to 1 hours after removal of the bleaching gel. Conclusions Both experimental groups presented satisfactorily lighter shades, but no statistically significant differences were observed regardless of the desensitization protocol employed. Clinical relevance The combined use of ozonated sunflower oil followed by a potassium nitrate and sodium fluoride-based desensitizing agent results in reduced sensitivity compared to the desensitizing agent alone.

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An in vitro analysis of the effect of adjunctive use of ozonated oil with a desensitizing agent on dentinal tubule occlusion

Cited by 11 publications

References 18 publications

Efficacy of Ozonized Sunflower Oil with Tea Tree Oil as Desensitizing Agents in Dental Bleaching: Randomized and Double-Blind Clinical Trial

Efficacy of Ozonized Sunflower Oil with Tea Tree Oil as Desensitizing Agents in Dental Bleaching: Randomized and Double-Blind Clinical Trial

Ozonated Oil as a Desensitizing Protocol in External Dental Bleaching: A Clinical, Randomized and Double-Blind Study

Evaluation of the ozonated sunflower oil application on reducing sensitivity after at-home bleaching

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