2011
DOI: 10.1055/s-0031-1282921
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An in vitro approach to neuroprotective activity of Rosa damascena Mill., a medieval age traditional medicine used for memory enhancement

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Cited by 9 publications
(7 citation statements)
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“…Previous studies report that rose essential oil (REO) possesses antioxidant properties, antibacterial, and antifungal activity, anti-inflammatory effects. Also, it seemed that R. damascena essential oil has an inhibitory effect on acetylcholine esterase (AChE) and butyrylcholine esterase (BChE) in vitro. The result seemed to reveal one of the reasons that REO is beneficial to improve memory impairment. , The previous works suggest that REO has the potential for treating Alzheimer’s disease (AD). However, the underlying pharmacological mechanisms of REO for anti-AD have been far from completely understood.…”
Section: Introductionmentioning
confidence: 94%
“…Previous studies report that rose essential oil (REO) possesses antioxidant properties, antibacterial, and antifungal activity, anti-inflammatory effects. Also, it seemed that R. damascena essential oil has an inhibitory effect on acetylcholine esterase (AChE) and butyrylcholine esterase (BChE) in vitro. The result seemed to reveal one of the reasons that REO is beneficial to improve memory impairment. , The previous works suggest that REO has the potential for treating Alzheimer’s disease (AD). However, the underlying pharmacological mechanisms of REO for anti-AD have been far from completely understood.…”
Section: Introductionmentioning
confidence: 94%
“…12 (8) 2017 1329 Rosa damascena has beneficial effects on brain function and has potential applications for the treatment of dementia. A recent study by our group has suggested that rose oil and a main component of the rose fragrance, phenylethyl alcohol, significantly inhibits acetylcholineesterase (AChE) and butyrylcholineesterase (BChE) suggesting neuroprotective and memory enhancement activities [25,26]; complementary studies by other scientists confirmed these findings [27][28][29].…”
Section: Citronellolmentioning
confidence: 85%
“…A is thought to be a major pathological cause of Alzheimer's disease. A (25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35), the major fragment of the full peptide Ab found in the brains of Alzheimer patients, causes neural cell death, neuritic atrophy, synaptic loss, and memory impairment [32].…”
Section: Rose In Ancient and Modern Civilizationsmentioning
confidence: 99%
“…31 Rosa damascena uçucu yağının hafıza üzerindeki etkileri deneysel çalışmalarla doğrulanmış, in vitro olarak asetilkolinesteraz ve butirilkolinesteraz üzerinde inhibe edici bir etkiye sahip olduğu ve bilişsel durumu iyileştirmek için yararlı olabileceği belirtilmiştir. 32 Gül uçucu yağının baş ağrısı ve migrende de etkili olduğu bildirilmiştir. 26,33 8-Vetiver uçucu yağı (Vetiverae aetheroleum) 2-3 metreye kadar uzayabilen, son derece derin ve yaygın yapılı bir kök sistemine sahip olan, bu kök sistemi ile bitkiyi toprağa sıkıca bağlayarak erozyonu önlemede kullanılan Vetiveria zizanioides (L.) Nash.…”
Section: -Gül Uçucu Yağı (Rosa Damascenae Aetheroleum)unclassified