An in vitro study of the antioxidant activities and effect on human DNA of the Chinese herbal decoction 'Liu Wei Di Huang'

Szeto, Yim Tong Savio; Lei, Pui-Cheong; Ngai, Kamleong; Yiu, Andy Tak-Wah; Chan, Catarina Sin-Pek; Kok, Edith Wun-Fong; Leong, Chi-Wa

doi:10.1080/09637480802012209

Cited by 6 publications

(9 citation statements)

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“…There are over 1000 active compounds in RF and considerable effort is required to investigate each one individually. Szeto et al 50 suggested that the function of a particular herb may disappear when it is used as part of a formula. Consequently, the functional use of one well-known herb or its compound cannot explain the effect of a formula that contains it.…”

Section: Discussionmentioning

confidence: 99%

“…There were 15 reports that listed the ratio of components in RF 6–9,11–14,19,27,32–34,46,50 . The weight of the different components making up RF is a major concern, because there were differences among these trials.…”

Section: Literature Reviewmentioning

confidence: 99%

“…48 Indirect evidence: oxidative stress. Szeto et al 50 demonstrated that RF had no effect on oxidative damage in isolated human lymphocytes, but that P. suffruticosa and D. batatas did. Another three studies investigated the antioxidative effects of P. suffruticosa.…”

Section: Herb (Dioscorea Opposita)mentioning

confidence: 99%

“…There were 15 reports that listed the ratio of components in RF. [6][7][8][9][11][12][13][14]19,27,[32][33][34]46,50 The weight of the different components making up RF is a major concern, because there were differences among these trials. From the ancient medical literature, the composition of RF is 24 g (Rehmannia radix):12 g (D. batatas):12 g (Fructus Corni):9 g (A. plantago):9 g (P. cocos):9 g (Cortex Moutan).…”

Section: Composition Of the Rf Formulamentioning

confidence: 99%

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Review of the effects of the traditional Chinese medicine Rehmannia Six Formula on diabetes mellitus and its complications

Poon

Ong

Cheung

2011

Journal of Diabetes

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Rehmannia Six Formula (RF) is a formula that is commonly used in Traditional Chinese Medicine to treat patients with diabetes. A literature search was performed in PubMed for the years 2000–2009 using the key words RF, Rehmannia glutinosa, Fructus Corni, Dioscorea sp. (D. alata, D. opposita, D. batatas), Poria cocos, Alisma sp. (A. orientalis, A. plantago aquatica), and Paeonia suffruticosa/Cortex Moutan. On the basis of the publications found, RF appears to have beneficial effects on blood glucose, neuropathy, and nephropathy. There is also evidence of anti‐inflammatory and antioxidant effects. Although there are many studies on compounds extracted from individual herbs, there are not many studies on RF as a whole. Because there is preliminary evidence that RF may be a useful supplement for the prevention of diabetic complications, clinical studies are warranted. For future clinical studies, it is recommended that details are provided regarding the preparation of RF and that the ratio of the individual components in RF is standardized so that results across studies can be compared.

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Section: Discussionmentioning

confidence: 99%

Section: Literature Reviewmentioning

confidence: 99%

Section: Herb (Dioscorea Opposita)mentioning

confidence: 99%

Section: Composition Of the Rf Formulamentioning

confidence: 99%

See 2 more Smart Citations

Review of the effects of the traditional Chinese medicine Rehmannia Six Formula on diabetes mellitus and its complications

Poon

Ong

Cheung

2011

Journal of Diabetes

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“…In a senescence accelerated mouse hippocampus, LWDH might facilitate cognition by genes' expressions (Chang et al, 2007). But H 2 O 2 induced DNA damage was suppressed by a single treatment of herbs that are components of LWDH, but LWDH as a herbal formula was not successful (Szeto et al, 2009). Also, Yang et al (2006) reported that LWDH suppressed K + and Ca 2+ ion currents in cultured rat hippocampal neurons, and Shin et al (2003) reported that shenqi wan diminished glutamate and NMDA receptor induced ion currents.…”

Section: Neuronal Disease In Traditional Medicinementioning

confidence: 99%

Brief comparison of the mechanism of modern medicine and traditional medicine in neuronal cell death

Kim¹,

Jeong²,

Kim³

et al. 2011

TANG [HUMANITAS MEDICINE]

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Medicine has a past, a present, and will have a future; the same can be said for many diseases. Even with the surprising development of modern medicine, traditional medicine, especially eastern Asian traditional medicines still exist and are widely used in those regions. But modern medicine and western pacific traditional medicines have different theories and applications for the same disease. In this review, traditional medical theory, used together with modern medicine, can be combined to shed light on the area of neuronal death.

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Growth-promoting Activity of Sanyak (Dioscoreae rhizoma) Extract on Injured Sciatic Nerve in Rats

Lee

Namgung

Hong

2009

Journal of Acupuncture and Meridian Studies

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The present study evaluates the potential effects of Sanyak (Dioscoreae rhizome) on the regenerative capacity of the peripheral sciatic nerve after crush injury in rats. Focal application of Sanyak extract at the injury site increased GAP-43 and Cdc2 protein levels in the distal portion of the injured nerve. Immunohistochemical analysis showed that the signals of phospho-vimentin as Cdc2 substrate protein were almost colocalized with Cdc2. Retrograde DiI-tracing revealed enhancement in distal elongation of regenerating axons. Furthermore, the number of non-neuronal cells was higher in Sanyak-treated animals than saline controls. Thus, these data suggest that Sanyak extract is effective for promoting regenerative responses in injured peripheral neurons.

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An in vitro study of the antioxidant activities and effect on human DNA of the Chinese herbal decoction 'Liu Wei Di Huang'

Cited by 6 publications

References 0 publications

Review of the effects of the traditional Chinese medicine Rehmannia Six Formula on diabetes mellitus and its complications

Review of the effects of the traditional Chinese medicine Rehmannia Six Formula on diabetes mellitus and its complications

Brief comparison of the mechanism of modern medicine and traditional medicine in neuronal cell death

Growth-promoting Activity of Sanyak (Dioscoreae rhizoma) Extract on Injured Sciatic Nerve in Rats

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