An increase in the serum amylase level in patients after peroral double-balloon enteroscopy: an association with the development of pancreatitis

Honda, Kazufumi; Itaba, Soichi; Mizutani, Tomohiro; Sumida, Yorinobu; Kanayama, Kenji; Higuchi, Naomi; Yoshinaga, Shigetaka; Akiho, Hirotada; Kawabe, Ken; Arita, Yoshiyuki; Ito, Tairo; Nakamura, Kazuhiko; Takayanagi, Ryoichi

doi:10.1055/s-2006-944831

Cited by 56 publications

(60 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Honda et al found asymptomatic hyperamylasemia in 5 of 13 patients after antegrade DBE. One of 13 patients developed pancreatitis [25] . Several mechanisms c o u l d b e r e s p o n s i b l e f o r t h e d e v e l o p m e n t o f hyperamylasemia or pancreatitis.…”

Section: Discussionmentioning

confidence: 99%

Double balloon endoscopy associated pancreatitis: A description of six cases

Jarbandhan

Weyenberg²,

Veer

et al. 2008

WJG

View full text Add to dashboard Cite

INTRODUCTIONSince its introduction in 2001 by Yamamoto [1] , double balloon endoscopy (DBE) has revolutionized both diagnostic and therapeutic small bowel endoscopy [2] . This technique allows (intervention) endoscopy of the complete small bowel (often in two sessions) with the possibility of carrying out interventions; e.g. mucosal biopsy, argon plasma coagulation, snare polypectomy, injection therapy, tattooing, foreign body extraction and balloon dilatation. DBE plays an important role in the diagnosis and treatment of obscure gastrointestinal bleeding [3][4][5][6] , Crohn's disease [7][8][9][10] , celiac disease [11,12] , polyposis syndromes [13] and small bowel tumors. In the series published to date, complications solely related to the diagnostic procedure are rare [14][15][16][17][18] . A recent retrospective multicenter survey indicates a complication rate of 0.8% in diagnostic procedures [16] . In that study, pancreatitis occurred in six of 2362 (0.3%) procedures and contributed to 46% of all complications after diagnostic DBE. Another recent study showed that an asymptomatic rise of serum amylase and lipase levels after antegrade DBE is frequently encountered [19] . Nevertheless, only a few patients develop the clinical picture of post-DBE pancreatitis. The reason for this remains unknown.This article presents an analysis of all DBE-related cases of pancreatitis identified prospectively from a recorded DBE-complication database of 603 procedures in a single center. RESULTS: This is the largest single-center study reporting on post-DBE pancreatitis prospectively. Six patients (1.0%) developed post-DBE pancreatitis, all after antegrade DBE. There was no association with gender, duration of the procedure or type of endoscope. The mean age was 51.9 years (range 25-78). Four patients had severe pancreatitis. Of these, two had inflammatory signs in the body-tail region, one had pancreatitis in the tail region, and the total pancreas was involved in one. MATERIALS AND METHODS From CONCLUSION:The incidence of post-DBE pancreatitis in our series is higher than previously reported. We found no relation with DBE-endoscope type. The inflammatory changes occurred in the body-tail region of the pancreas, suggesting that post-DBE pancreatitis is caused by repetitive mechanical strain on the pancreas.

show abstract

Section: Discussionmentioning

confidence: 99%

Double balloon endoscopy associated pancreatitis: A description of six cases

Jarbandhan

Weyenberg²,

Veer

et al. 2008

WJG

View full text Add to dashboard Cite

show abstract

“…Diagnostic DBE is accompanied by complications in < 1 % of cases. Hyperamylasaemia has been documented in up to 50 % of patients [157], but clinically significant pancreatitis occurs in only 1 %, almost exclusively after use of the oral insertion route [158,159]. Therapeutic balloon enteroscopy with balloon dilation of strictures has a reported perforation risk of 0 % -3 %, which is comparable to dilation of colonic Crohnʼs strictures [160,161].…”

Section: Balloon-assisted Enteroscopy (Bae)mentioning

confidence: 99%

Role of small-bowel endoscopy in the management of patients with inflammatory bowel disease: an international OMED–ECCO consensus

Bourreille¹,

Ignjatovic²,

Aabakken³

et al. 2009

Endoscopy

304

185

View full text Add to dashboard Cite

show abstract

“…None of the eight patients undergoing retrograde DBE showed elevations of pancreatic enzymes, whereas enzyme elevations were observed in 12 of the 48 patients (25%), six of them being hospitalized due to frank pancreatitis after antegrade DBEs. Honda et al (25), who reported their experience with 13 patients, found that six of them (46%) developed pancreatic enzyme elevations and one developed acute pancreatitis, but this finding and its implications are addressed in a separate study.…”

Section: Discussionmentioning

confidence: 98%

Double-balloon enteroscopy: The diagnosis and management of small bowel diseases

Pata

Akyüz²,

Erzın³

et al. 2010

Turk J Gastroenterol

View full text Add to dashboard Cite

An increase in the serum amylase level in patients after peroral double-balloon enteroscopy: an association with the development of pancreatitis

Abstract: Hyperamylasemia after peroral DBE occurs frequently and may be associated with development of pancreatitis.

Cited by 56 publications

References 7 publications

Double balloon endoscopy associated pancreatitis: A description of six cases

Double balloon endoscopy associated pancreatitis: A description of six cases

Role of small-bowel endoscopy in the management of patients with inflammatory bowel disease: an international OMED–ECCO consensus

Double-balloon enteroscopy: The diagnosis and management of small bowel diseases

Contact Info

Product

Resources

About