The development of industrial-enabling technology, such as the industrial Internet of Things and physical network system, makes it possible to use real-time information in production-logistics scheduling. Real-time information in an intelligent factory is random, such as the arrival of customers’ jobs, and fuzzy, such as the processing time of Production-Logistics Resources. Besides, the coordination of production and logistic resources in a flexible workshop is also a hot issue. The availability of this information will enhance the quality of making scheduling decisions. However, when and how to use this information to realize the adaptive collaboration of Production-Logistics Resources are vital issues. Therefore, this paper studies the above problems by establishing a real-time reaction scheduling framework of Production-Logistics Resources dynamic cooperation. Firstly, a real-time task triggering strategy to maximize information utilization is proposed to explore when to use real-time information. Secondly, a collaborative method for Production-Logistics Resources is studied to explore how to use real-time information. Thirdly, a real-time self-adaptive scheduling algorithm based on information entropy is utilized to obtain a stable and feasible solution. Finally, the effectiveness and advancement of the proposed method are verified by a practical case.