2012
DOI: 10.1016/j.biomaterials.2012.01.004
|View full text |Cite
|
Sign up to set email alerts
|

An injectable biodegradable temperature-responsive gel with an adjustable persistence window

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
30
0

Year Published

2014
2014
2024
2024

Publication Types

Select...
7
1

Relationship

3
5

Authors

Journals

citations
Cited by 50 publications
(30 citation statements)
references
References 21 publications
0
30
0
Order By: Relevance
“…In a complementary study by the same group 6 families of differing CL/LLA ratios were synthesised and in some cases, pendant groups were attached. 53 These pendant groups were attached on the LLA units and they were either 3-benzyloxymethyl lactide (BnLA) units or their hydroxyl and carboxyl derivatives and they observed that the introduction of side groups disturbs the gelation possibly because it prevents the CL crystallinity thus the T gel increased compared with the non-modified polymers. Interestingly, when comparing the hydrophobicity/hydrophilicity of the pendant groups between them the more hydrophobic were able to affect the CL crystallinity more and thus the polymers with hydrophobic side groups presented higher T gel s than the ones with hydrophilic side groups.…”
Section: Effect Of Composition/ Hydrophobicitymentioning
confidence: 99%
See 2 more Smart Citations
“…In a complementary study by the same group 6 families of differing CL/LLA ratios were synthesised and in some cases, pendant groups were attached. 53 These pendant groups were attached on the LLA units and they were either 3-benzyloxymethyl lactide (BnLA) units or their hydroxyl and carboxyl derivatives and they observed that the introduction of side groups disturbs the gelation possibly because it prevents the CL crystallinity thus the T gel increased compared with the non-modified polymers. Interestingly, when comparing the hydrophobicity/hydrophilicity of the pendant groups between them the more hydrophobic were able to affect the CL crystallinity more and thus the polymers with hydrophobic side groups presented higher T gel s than the ones with hydrophilic side groups.…”
Section: Effect Of Composition/ Hydrophobicitymentioning
confidence: 99%
“…Interestingly, when comparing the hydrophobicity/hydrophilicity of the pendant groups between them the more hydrophobic were able to affect the CL crystallinity more and thus the polymers with hydrophobic side groups presented higher T gel s than the ones with hydrophilic side groups. 53 In all the following studies the hydrophobicity was varied by not changing the ratio of the hydrophobic/hydrophilic units but by fabricating different polymers where the thermoresponsive units were kept the same but the comonomer was changed.…”
Section: Effect Of Composition/ Hydrophobicitymentioning
confidence: 99%
See 1 more Smart Citation
“…In a later study, we prepared thermogelling diblock copolymers using benzyl, hydroxyl or carboxylic acid groups in the pendant-position derivatization of diblock copolymers [19]. We found that intra-and inter-molecular interactions among hydrophobic PCL segments can stabilize or destabilize aggregation depending on functional pendant groups.…”
Section: Introductionmentioning
confidence: 96%
“…12 Furthermore, preparing the MPC solution required approximately 20 min. Therefore, we concluded that if the hydrophobic PCL block is extremely long, the polymer in aqueous solutions cannot undergo a sol-to-gel transition because of its low solubility.…”
Section: Introductionmentioning
confidence: 99%