An injectable hydroxyapatite/poly(lactide-co-glycolide) composite reinforced by micro/nano-hybrid poly(glycolide) fibers for bone repair

Zhu, Yuhang; Wang, Zongliang; Zhou, Hongli; Li, Linlong; Zhu, Qiang; Zhang, Peibiao

doi:10.1016/j.msec.2017.04.121

Cited by 26 publications

(19 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Using such bers, we have fabricated three-dimensional scaffolds for bone tissue engineering in our laboratory. [24][25][26] Mechanical properties…”

Section: Morphology and Diametersmentioning

confidence: 99%

Cotton-like micro- and nanoscale poly(lactic acid) nonwoven fibers fabricated by centrifugal melt-spinning for tissue engineering

et al. 2018

Self Cite

View full text Add to dashboard Cite

show abstract

“…Using such bers, we have fabricated three-dimensional scaffolds for bone tissue engineering in our laboratory. [24][25][26] Mechanical properties…”

Section: Morphology and Diametersmentioning

confidence: 99%

Cotton-like micro- and nanoscale poly(lactic acid) nonwoven fibers fabricated by centrifugal melt-spinning for tissue engineering

et al. 2018

Self Cite

View full text Add to dashboard Cite

show abstract

“…This method develops biodegradable and bioactive polymer-ceramic composites conducive for the use of bone tissue scaffolds [ 152 ]. Polymer composites can be formulated by incorporating micro/nano scale hydroxyapatites (HA) or calcium phosphate particles (more commonly, β-TCP) due to their biomimetic and osteogenic properties [ 153 , 154 ]. Besides ceramics, several inorganic/organic constituents, such as carbon nanotubes, nanoparticles, nanospheres, nanoshells, etc.…”

Section: Principle Of Electrospinningmentioning

confidence: 99%

A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue Engineering

2018

View full text Add to dashboard Cite

Bone tissue engineering is an interdisciplinary field where the principles of engineering are applied on bone-related biochemical reactions. Scaffolds, cells, growth factors, and their interrelation in microenvironment are the major concerns in bone tissue engineering. Among many alternatives, electrospinning is a promising and versatile technique that is used to fabricate polymer fibrous scaffolds for bone tissue engineering applications. Copolymerization and polymer blending is a promising strategic way in purpose of getting synergistic and additive effect achieved from either polymer. In this review, we summarize the basic chemistry of bone, principle of electrospinning, and polymers that are used in bone tissue engineering. Particular attention will be given on biomechanical properties and biological activities of these electrospun fibers. This review will cover the fundamental basis of cell adhesion, differentiation, and proliferation of the electrospun fibers in bone tissue scaffolds. In the last section, we offer the current development and future perspectives on the use of electrospun mats in bone tissue engineering.

show abstract

“…In addition, GAG [90] was introduced to promote scaffold, cellular and biological cue interactions as it has strong affinity to growth factors for directing cell fate. PLA [91], PLGA [92], PCL [93] and polyurethane (PU) [94] are popular synthetic biomaterials for bone/cartilage tissue engineering. Among them, PCL stood out for its superior short-term and long-term biocompatibility due to non-inflammatory and nontoxic degradation products [[145], [146], [147]], unlike acid-releasing PLA and PLGA.…”

Section: Biomaterials and Stem Cell Applicationsmentioning

confidence: 99%

Biomaterials for stem cell engineering and biomanufacturing

Chen

Hellwarth

et al. 2019

Bioactive Materials

View full text Add to dashboard Cite

Recent years have witnessed the expansion of tissue failures and diseases. The uprising of regenerative medicine converges the sight onto stem cell-biomaterial based therapy. Tissue engineering and regenerative medicine proposes the strategy of constructing spatially, mechanically, chemically and biologically designed biomaterials for stem cells to grow and differentiate. Therefore, this paper summarized the basic properties of embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs) and adult stem cells. The properties of frequently used biomaterials were also described in terms of natural and synthetic origins. Particularly, the combination of stem cells and biomaterials for tissue repair applications was reviewed in terms of nervous, cardiovascular, pancreatic, hematopoietic and musculoskeletal system. Finally, stem-cell-related biomanufacturing was envisioned and the novel biofabrication technologies were discussed, enlightening a promising route for the future advancement of large-scale stem cell-biomaterial based therapeutic manufacturing.

show abstract

An injectable hydroxyapatite/poly(lactide-co-glycolide) composite reinforced by micro/nano-hybrid poly(glycolide) fibers for bone repair

Cited by 26 publications

References 44 publications

Cotton-like micro- and nanoscale poly(lactic acid) nonwoven fibers fabricated by centrifugal melt-spinning for tissue engineering

Cotton-like micro- and nanoscale poly(lactic acid) nonwoven fibers fabricated by centrifugal melt-spinning for tissue engineering

A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue Engineering

Biomaterials for stem cell engineering and biomanufacturing

Contact Info

Product

Resources

About