An innovative all-polymeric drug-supply device

Abstract

In this paper, we report an innovative all-polymeric drug-supply device. The micro outlet of the device was ablated through a polymethyl methacrylate (PMMA) layer using a microheater. The size of the ablated micropore was mainly related to the heater temperature profile, and the molten PMMA took the gold heater lines away from the pore area, avoiding possible block of the gold lines to the flow out of the pore. Simulation was conducted to find the temperature profile on the surface of the microheater, and experimental results have a good match with simulation results.