An Insidious Disaster Composed of Sinusitis, Myocarditis, Lung Mass And Rapidly Progressive Glomerulonephritis: Wegener Granulomatosis

Abstract

Wegener's Granulomatosis is a multisystemic granulomatous inflammation of small vessels that typically effects the kidney, skin, joints and lower and upper airway tracts. Because of the multisystemic involvement, the signs and symptoms of disease may arise in heterogeneous fashion. Under the appearance of a nonspecific sytemic complaints, the suspicion of clinician may be a final clue for diagnosis. Here we present a patient with Wegener's granolomatosis sufferring from generalized malaise, fever, heart failure, lung mass and acute renal failure. Multidisciplinary and close colloborative management is important to establish early diagnosis. We belive that plasmapheresis at initial acute onset of vasculitis syndromes especially in severe extrarenal involvements may be a lifesaving management.

Unusual Case Presentations of Wegener’s Granulomatosis

“…WG is a rare systemic disorder and affected patients may seek help from physicians of diverse specialties (3). Clinical symptoms and organ involvement of the disease vary widely.…”

“…Clinical symptoms and organ involvement of the disease vary widely (2,3). Rapidly progressive deterioration of renal function is a frequent but clinically unfavorable feature of WG (4).…”