2023
DOI: 10.2174/1570179420666230316094435
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An Insight on the Prospect of Quinazoline and Quinazolinone Derivatives as Anti-tubercular Agents

Abstract: Multiple potential drugs have been developed based on the heterocyclic molecules for the treatment of different symptoms. Among the existing heterocyclic molecules, quinazoline and quinazolinone derivatives have been found to exhibit extensive pharmacological and biological characteristics. One significant property of these molecules is their potency as anti-tubercular agents. Thus, both quinazoline and quinazolinone derivatives are modified using different functional groups as substituents for investigating t… Show more

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Cited by 7 publications
(1 citation statement)
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“…Quinazolinones are nitrogenous bicyclic aromatic molecules and important biologically active nitrogen heterocycles. Their derivatives exhibit a wide range of biological activities, including antibacterial, 1 anticancer, 2 antiviral, 3 antitubercular, 4,5 anticonvulsant, 6 anti-inflammatory, 7 antihypertensive, 8 antitumor, 9,10 and antidiabetic 11 activities. The synthesis of quinazolinones has attracted considerable research interest because of their multiple pharmacological activities.…”
Section: Introductionmentioning
confidence: 99%
“…Quinazolinones are nitrogenous bicyclic aromatic molecules and important biologically active nitrogen heterocycles. Their derivatives exhibit a wide range of biological activities, including antibacterial, 1 anticancer, 2 antiviral, 3 antitubercular, 4,5 anticonvulsant, 6 anti-inflammatory, 7 antihypertensive, 8 antitumor, 9,10 and antidiabetic 11 activities. The synthesis of quinazolinones has attracted considerable research interest because of their multiple pharmacological activities.…”
Section: Introductionmentioning
confidence: 99%