An Institutional Study of the Salivary Gland Neoplasms: A Case Series and Review of Literature

Abstract

Objective: Different geographic areas show different frequency and incidence of salivary gland tumors (SGTs) and understanding such a demographic data is useful in knowing the nature of the salivary gland neoplasms worldwide. Not only the demographic data but also the clinical site of occurrence of the tumor, radiological features, staining and IHC are helpful in improving the comprehension of the clinicopathologic characteristics of the SGTs. The aim of the study was to determine the distribution and demographic features of the SGTs in West Godavari, Andhra Pradesh population, India. Study design: Retrospectively analysis of the clinico-pathological features of all the histologically diagnosed salivary gland tumors of the past 20 years (2002-2022) from the institutional archives with demographic data and site of occurrence was retrieved. This will add information on the diagnosis in the upcoming neoplasms. The study design presents the demographic details which may provide insight of the SGTs worldwide. Cases presentation: All the relevant demographic and histopathological information regarding the diagnosed cases of salivary gland tumors were retrieved from archival files of the Department of oral pathology, Vishnu Dental College, Bhimavaram, West Godavari, Andhra Pradesh and correlated for clinico-pathological findings. The histological features were re-examined for the assessment of the grade and necessary special staining were performed. The present study analyzed 43 SGTs among them 12were pleomorphic adenoma, 15 were MECs, 7 were ACCs, 2 myoepitheliomas, 2 adenocarcinomas (of which one was metastatic carcinoma of the mandible), 1 epithelial myoepithelial carcinoma, 1 intra osseous carcinoma, 1 salivary duct carcinoma, 1 depicting both the features of PLGA and adenoid cystic carcinoma and 1 depicting both the features of adenoid cystic carcinoma and epimyoepithelial carcinoma.