2022
DOI: 10.1038/s41586-022-05306-8
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An integrated imaging sensor for aberration-corrected 3D photography

Abstract: Planar digital image sensors facilitate broad applications in a wide range of areas1–5, and the number of pixels has scaled up rapidly in recent years2,6. However, the practical performance of imaging systems is fundamentally limited by spatially nonuniform optical aberrations originating from imperfect lenses or environmental disturbances7,8. Here we propose an integrated scanning light-field imaging sensor, termed a meta-imaging sensor, to achieve high-speed aberration-corrected three-dimensional photography… Show more

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Cited by 82 publications
(31 citation statements)
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“…To meet the pressing demand, various efforts have been invested during the past decades to develop fast and high-quality volumetric imaging methods [13][14][15][16], among which light-field microscopy (LFM) [17] is an attractive candidate due to its high parallelization and low phototoxicity. By inserting a microlens array (MLA) into the detection path, LFM encodes the high-dimensional information of a large volume in a snapshot, providing a powerful capability of high-speed 3D imaging [18][19][20]. However, similar to common microscopy techniques, LFM still suffers from the tradeoff between spatial-temporal resolution and the volume coverage, which impedes observing subtle details in large-scale volumes.…”
Section: Introductionmentioning
confidence: 99%
“…To meet the pressing demand, various efforts have been invested during the past decades to develop fast and high-quality volumetric imaging methods [13][14][15][16], among which light-field microscopy (LFM) [17] is an attractive candidate due to its high parallelization and low phototoxicity. By inserting a microlens array (MLA) into the detection path, LFM encodes the high-dimensional information of a large volume in a snapshot, providing a powerful capability of high-speed 3D imaging [18][19][20]. However, similar to common microscopy techniques, LFM still suffers from the tradeoff between spatial-temporal resolution and the volume coverage, which impedes observing subtle details in large-scale volumes.…”
Section: Introductionmentioning
confidence: 99%
“…By jointly optimizing computation and optics, computational imaging [1] improves the efficiency and information capacity of optical systems [2]. With computational imaging, one can achieve detection under extremely complex lighting conditions [3,4], capture invisible high-dimensional information [4][5][6], look through obstacles [7,8], etc.…”
Section: Introductionmentioning
confidence: 99%
“…Although numerous reconstruction algorithms have been developed to enable the practical and versatile application of LFM in biology [21][22][23][24][25][26][27] , LFM is still hindered by low spatial resolution and reconstruction artifacts, especially in complicated intravital environments. By introducing periodic beam drifting to increase the spatial sampling density, scanning LFM (sLFM) increases the resolution up to the diffraction limit and facilitates multi-site aberration correction in post-processing 28 , but the physical scanning process reduces the 3D imaging speed and may introduce motion artifacts for highly dynamic samples 20 .…”
mentioning
confidence: 99%