An integrated in-silico approach for drug target identification in human pathogen Shigella dysenteriae
Hurria Qureshi,
Amina Basheer,
Wasim Sajjad
et al.
Abstract:Shigella dysenteriae, is a Gram-negative bacterium that emerged as the second most significant cause of bacillary dysentery. Antibiotic treatment is vital in lowering Shigella infection rates, yet the growing global resistance to broad-spectrum antibiotics poses a significant challenge. The persistent multidrug resistance of S. dysenteriae complicates its management and control. Hence, there is an urgent requirement to discover novel therapeutic targets and potent medications to prevent and treat this disease.… Show more
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