An integrated laser blood flowmeter

Higurashi, Eiji; Sawada, Renshi; Ito, Toshio

doi:10.1109/jlt.2003.809551

Cited by 67 publications

(41 citation statements)

References 13 publications

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“…This probe is commercially available as the Diodopp (Applied Laser Technologies, The Netherlands). Higurashi et al [45] reported on a lighter and smaller integrated probe (1.5 mm thick×2 mm wide×3 mm long) in which they used a more compact InGaAsP-InP distributed feedback laser diode (1,310 nm). owing to the edge-emitting behavior of the latter, a micromachined concave mirror was required for beam deflection.…”

Section: Integrated Systemsmentioning

confidence: 99%

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Review of methodological developments in laser Doppler flowmetry

et al. 2008

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Section: Integrated Systemsmentioning

confidence: 99%

“…Commercial laser Doppler systems use a high-pass filter (often 20 Hz) to filter out the low-frequency part of spectra, to deal with motion artifacts. The problem of fiber-based noise from movement artifacts can be solved with the use of an integrated probe [44][45][46], where light delivery and detection are on the same probe.…”

Section: Motion Artifactsmentioning

confidence: 99%

Review of methodological developments in laser Doppler flowmetry

et al. 2008

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“…Then, blood flow in both great toes was measured. The MILDF [11][12][13] used in this study was a box type that measured 5.6 mm × 12.0 mm × 17.5 mm and weighed 3 g (Fig. 1).…”

Section: Methodsmentioning

confidence: 99%

“…A micro wireless flowmeter integrated laser Doppler blood flowmeter (MILDF) has been developed. [11][12][13] MILDF provides similar results to measurement of blood flow with conventional LDF. In addition, MILDF is wireless, portable, and allows monitoring of diurnal blood flow variation.…”

mentioning

confidence: 95%

Correlation between Changes in Leg Blood Flow and Ankle-Brachial Pressure Index: A Study Using Laser Doppler Flowmeter —The 1st Report—

Suzuki

Sekiguchi

Midorikawa

et al. 2011

Annals of Vascular Diseases

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Objective: The objective of this study was to use non-invasive laser Doppler flowmeter to measure changes in blood flow in peripheral vessels in the legs before and after stress induced by leg elevation stress test and investigate correlations with the ankle-brachial pressure index (ABI). Methods: Subjects included 28 patients over 20 years of age (mean, 73 years) who reported chiefly of leg symptoms such as intermittent claudication, numbness, chills, or cramps had been examined at the study institution, and agreed to participate in the study. The ABI of both legs was measured, and patients were divided into two groups: low ABI (ABI ≤0.9) and normal ABI (ABI ≥0.9). Blood flow in the big toe was measured using a box-type laser Doppler flowmeter before, during, and after leg-elevation stress. Amplitude of the recorded waveform and changes in blood flow were compared. Results: Average ABI was 1.09 ± 0.10 in the normal ABI group (33 legs) and 0.68 ± 0.17 in the low ABI group (21 legs). Amplitude before and during stress was significantly smaller in the low ABI group than in the normal ABI group ( p <0.01), and there was a significant correlation with ABI before and during stresses (r = 0.4606, r = 0.5048, respectively; p <0.05). Change in blood flow during stress was significantly lower in the low ABI group than in the normal ABI group ( p <0.05). There was a significant correlation between change in blood flow during stress and ABI in both groups (r = 0.5073; p <0.05). There was also a significant correlation between change in blood flow and change in amplitude in both groups (r = 0.5477; p <0.05). Conclusion: Results of this study show, that comparing amplitude and change in blood flow before and after leg extension and elevation stress, there was a correlation between change in blood flow and amplitude, and ABI during stress. A box-type laser Doppler flowmeter may provide a means of screening for peripheral arterial disease.

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“…The aim was to create devices that integrate all the optical components of the laser Doppler flowmeter. This approach allows avoiding the main drawback affecting the most common techniques used to conduct the laser light in the site of measurement and from the site to the photodetector (e.g., by a fiber optic): i.e., the need of alignment between individual optical components [76].…”

Section:  Laser Doppler Flowmetermentioning

confidence: 99%

Micromachined Flow Sensors in Biomedical Applications

2012

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Application fields of micromachined devices are growing very rapidly due to the continuous improvement of three dimensional technologies of micro-fabrication. In particular, applications of micromachined sensors to monitor gas and liquid flows hold immense potential because of their valuable characteristics (e.g., low energy consumption, relatively good accuracy, the ability to measure very small flow, and small size). Moreover, the feedback provided by integrating microflow sensors to micro mass flow controllers is essential to deliver accurately set target small flows. This paper is a review of some application areas in the biomedical field of micromachined flow sensors, such as blood flow, respiratory monitoring, and drug delivery among others. Particular attention is dedicated to the description of the measurement principles utilized in early and current research. Finally, some observations about characteristics and issues of these devices are also reported.

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An integrated laser blood flowmeter

Cited by 67 publications

References 13 publications

Review of methodological developments in laser Doppler flowmetry

Review of methodological developments in laser Doppler flowmetry

Correlation between Changes in Leg Blood Flow and Ankle-Brachial Pressure Index: A Study Using Laser Doppler Flowmeter —The 1st Report—

Micromachined Flow Sensors in Biomedical Applications

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