2023
DOI: 10.3389/fmed.2023.1155426
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An integrated machine learning predictive scheme for longitudinal laboratory data to evaluate the factors determining renal function changes in patients with different chronic kidney disease stages

Ming-Hsien Tsai,
Mao-Jhen Jhou,
Tzu-Chi Liu
et al.

Abstract: Background and objectivesChronic kidney disease (CKD) is a global health concern. This study aims to identify key factors associated with renal function changes using the proposed machine learning and important variable selection (ML&IVS) scheme on longitudinal laboratory data. The goal is to predict changes in the estimated glomerular filtration rate (eGFR) in a cohort of patients with CKD stages 3–5.DesignA retrospective cohort study.Setting and participantsA total of 710 outpatients who presented wi… Show more

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“…Following this, a backward elimination strategy is implemented, where these basic functions are systematically removed. The aim of this backward phase is to refine and optimize the combinations of the remaining knots, ensuring that the most effective and representative model is achieved [45].…”
Section: Marsmentioning
confidence: 99%
“…Following this, a backward elimination strategy is implemented, where these basic functions are systematically removed. The aim of this backward phase is to refine and optimize the combinations of the remaining knots, ensuring that the most effective and representative model is achieved [45].…”
Section: Marsmentioning
confidence: 99%
“…Finally, studying the local characteristics and differentiated development strategies of rural areas can provide useful experience and inspiration for the practice of rural ecological construction and carbon neutrality. Successful cases and experiences in different regions can learn from each other and promote the sustainable development of rural areas Tsai et al (2023). In addition, research can also provide reference for government policy-making and planning, promoting the implementation of rural ecological civilization construction and carbon neutrality goals.…”
Section: Local Characteristics and Differentiated Developmentmentioning
confidence: 99%