2020
DOI: 10.3390/ijms21062191
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An Intelligent Optimization Algorithm for Constructing a DNA Storage Code: NOL-HHO

Abstract: The high density, large capacity, and long-term stability of DNA molecules make them an emerging storage medium that is especially suitable for the long-term storage of large datasets. The DNA sequences used in storage need to consider relevant constraints to avoid nonspecific hybridization reactions, such as the No-runlength constraint, GC-content, and the Hamming distance. In this work, a new nonlinear control parameter strategy and a random opposition-based learning strategy were used to improve the Harris … Show more

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Cited by 36 publications
(21 citation statements)
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“…Moreover, in their work [33], the authors predicted the slope stability by utilizing HHO and k-fold cross-validation. Yin et al proposed a new control parameter method to HHO and random OBL to construct DNA storage [18]. Recently, the authors in [34] introduced a four strategies technique, including the OBL strategy, to improve HHO transition rules.…”
Section: Related Workmentioning
confidence: 99%
See 2 more Smart Citations
“…Moreover, in their work [33], the authors predicted the slope stability by utilizing HHO and k-fold cross-validation. Yin et al proposed a new control parameter method to HHO and random OBL to construct DNA storage [18]. Recently, the authors in [34] introduced a four strategies technique, including the OBL strategy, to improve HHO transition rules.…”
Section: Related Workmentioning
confidence: 99%
“…Algorithm 2: IHHO algorithm Input: N: population size, T: maximum number of iterations. Output: The rabbit location( ), potential rabbit location ( ) and their fitness values Initialize the population randomly ( = 1,2, … , ) Find the best opposite solutions based on EOBL, then select the fittest solutions, according to Equation (16), Equation 17and Equation (18). While (maximum iteration not reached ( < )) do…”
Section: Improved Harris Hawks Algorithm (Ihho)mentioning
confidence: 99%
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“…In 2020, to decrease the error rate, Cao et al (2020) presented a new constraint, namely, uncorrelated address, and constructed a set of effective DNA codes. Yin et al (2020) considered multiple constraints to ensure accurate hybridization of DNA sequences.…”
Section: Introductionmentioning
confidence: 99%
“…Since Dr. Adleman of the United States used DNA molecular biological computing to solve the directed path problem of seven nodes [ 1 ] in 1994, DNA computing has attracted the attention of researchers across the world [ 2 – 5 ]. In DNA computing, DNA nucleotide bases A, C, G, and T coding sequences are used as carriers of information; it has great advantages in dealing with large storage capacity, parallelism, and energy consumption of information [ 6 9 ]. DNA computing essentially uses biochemical experiments to address practical problems.…”
Section: Introductionmentioning
confidence: 99%