The paper presents a methodology for the assessment of the permissibility of the risk of changing the strategy for the maintenance of rail vehicles based on the example of a 6Dg diesel locomotive. The example of implementation has been preceded with the characteristics of the general formal requirements involved in the risk management process in accordance with the Commission Implementing Regulation (EU) No. 402/2013. The methodology which has been developed demonstrates that in order to appropriately quantify the frequency of occurrence of hazards (hazardous failures in particular) and adopt the correct risk assessment criteria, it is necessary to perform the reliability, availability, maintainability, safety analysis in the area of safety. Using the example and based on the reliability data gathered during the 15 months of operation of 75 locomotives, selected safety ratios for the locomotive's assemblies and subassemblies were determined whose failures lead to hazards to reliability and safety of rail transport. In order to qualify the risk involved in the occurrence of the hazards, one of the methods of estimating the explicit risk – the failure mode and effects analysis (FMEA) – was applied. The analysis demonstrated the possibility of and conditions for the introduction of changes in the maintenance strategy which would not be in breach of the acceptable risk level.