Extant research has addressed the challenges pertaining to sustainable freight transportation and those associated with transportation of perishable commodities in disparate ways in that enablers of sustainable freight transportation have not been mapped with the considerations of transportation related to perishable commodities. This is characterized by short product life-cycles, retail demand uncertainties, traceability issues and so forth. In this backdrop, the authors' research attempts to integrate the considerations related to sustainable freight transportation with that of perishability-related aspects. To this end, this research employs interpretive structural modelling (ISM) so that enablers related to both the problems can be fused and modeled in such a way that enablers related to independent, autonomous, dependent, and linkage attributes can be identified, and their interactions can be understood.