In this paper, in order to characterize optimality of a class of nonconvex differentiable multiobjective programming problems, we introduce two new types of vector variational-like inequalities, namely, a weak variational E-inequality and a vector variational E-inequality. Namely, under (strictly) E-convexity, we prove relationships between the aforesaid vector variational-like inequalities and differentiable vector optimization problems. Further, under (strictly) pseudo-E-convexity, we are in position to identify vector critical E-points, weak E-Pareto (E-Pareto) solutions of differentiable vector optimization problems and solutions of these introduced vector variational-like inequalities.