An Introduction to a Head and Neck Cancer-Specific Frailty Index and Its Clinical Implications in Elderly Patients: A Prospective Observational Study Focusing on Respiratory and Swallowing Functions

Kwon, Minsu; Kim, Shinae; Roh, Jong–Lyel; Lee, Sangwook; Kim, Sung‐Bae; Choi, Seung‐Ho; Nam, Soon Yuhl; Kim, Sang Yoon

doi:10.1634/theoncologist.2016-0008

Cited by 39 publications

(34 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A further 7 of 95 studies had at least one aspect of methodological quality rated as good; hypothesis testing was the measurement property with the highest number of good ratings (4 of 7). Overall, 70 of 95 studies had at least one aspect of methodological quality rated as fair 3,9,26,27,40,42,43,45,46,49–58,60,62,64,67–70,72–75,79–85,87–97,99–101,104,105,107–116,118,122,123,125–127 . Hypothesis testing had the greatest number of fair ratings (65 of 70).…”

Section: Resultsmentioning

confidence: 99%

“…Eleven of 48 tools include items from existing psychiatric assessment tools, five of which use items from the Centre for Epidemiological Studies‐Depression Scale (CES‐D) . Other tools included the Hospital Anxiety and Depression Scale (HADS) and the Beck Depression Inventory II . However, in most of these cases, items included from existing mental health tools were used to assess fatigue (6 of 12), rather than the presence of mental illness (5 of 12) …”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Multicomponent Frailty Assessment Tools for Older People with Psychiatric Disorders: A Systematic Review

Sutton

Gould

Coulson

et al. 2018

J American Geriatrics Society

View full text Add to dashboard Cite

Objective To review evidence evaluating the use of multicomponent frailty assessment tools in assessing frailty in older adults with psychiatric disorders. Methods A systematic literature review was conducted to identify all multicomponent frailty assessment tools (ie, a tool that assesses two or more indicators of frailty). The items of each frailty assessment tool were compared with Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM‐5) diagnostic criteria for psychiatric disorders to assess construct overlap. Studies conducted in community, inpatient, and outpatient clinical settings were considered for inclusion. Participants Adults aged 60 years or older. Results A total of 5639 records were identified following the removal of duplicates, from which 95 studies were included for review. Of the 48 multicomponent frailty assessment tools identified, no tool had been developed for, or validated in, older adult populations with a psychiatric disorder. Overall, 20 of 48 frailty assessment tools contained a psychological assessment domain, with 17 of 48 tools citing the presence of depressed mood and/or anxiety as a frailty indicator. Common areas of construct overlap in frailty assessment tools and DSM‐5 diagnostic criteria included weight loss (29 of 48) and fatigue (21 of 48). Conclusions Significant construct overlap exists between the indicators of frailty as conceptualized in existing frailty assessment tools and DSM‐5 diagnostic criteria for common psychiatric disorders including major depressive episode and generalized anxiety disorder that has the potential to confound frailty assessment results. Further research is necessary to establish a reliable and valid tool to assess frailty in this population. J Am Geriatr Soc 67:1085–1095, 2019.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Multicomponent Frailty Assessment Tools for Older People with Psychiatric Disorders: A Systematic Review

Sutton

Gould

Coulson

et al. 2018

J American Geriatrics Society

View full text Add to dashboard Cite

show abstract

“…Thus, dysphagia must be identified at an early stage and patients provided with nasogastric tube feeding to avoid pulmonary complications. This was underscored in a recent article that demonstrated that pretreatment swallowing and respiratory dysfunctions in elderly patients with head and neck cancer significantly impact early post‐treatment morbidity and mortality, and that frailty assessment comprising these functions has a greater prognostic significance than conventional screening methods to assess fitness for surgery . However, dysphagia and aspiration has not been reported to be a problem in the reviewed articles.…”

Section: Discussionmentioning

confidence: 99%

Transoral laser microsurgery for glottic cancer in the elderly: Efficacy and safety

et al. 2019

View full text Add to dashboard Cite

Background Data about the results of transoral laser microsurgery (TLM) in elderly patients are limited. Methods A retrospective study of 72 consecutive cases of glottic carcinoma (63 pT1 and 9 pT2 cases) in elderly patients (≥70 years old, mean 76 years) treated with TLM was made. A systematic review of the literature was performed. Results Six patients (8%) had postoperative complications, but no treatment‐related deaths were observed. Local recurrences occurred in 12 patients (16.5%): nine with pT1 (14%) and three with pT2 (33%) tumors. Five‐year disease‐specific survival (DSS), overall survival, and laryngectomy‐free survival were 95%, 68%, and 88%, respectively. The literature review indicated that TLM is safe and effective treatment for these patients, with few complications and good local control (>85%) and DSS (>90%) rates. Conclusions Our results and the information from the literature show that TLM for glottic cancer in elderly patients can lead to satisfactory treatment results.

show abstract

“…Anderson Dysphagia Index (MDADI) that were more predictive of 2-year morbidity and mortality than a “traditional” GA at baseline. 32 …”

Section: Methodsmentioning

confidence: 99%

The Older Adult With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: Knowledge Gaps and Future Direction in Assessment and Treatment

Maggiore

Zumsteg

BrintzenhofeSzoc

et al. 2017

International Journal of Radiation Oncology*Biology*Physics

View full text Add to dashboard Cite

Older adults with squamous cell carcinomas of the head and neck (HNSCC) pose unique treatment and supportive care challenges to oncologists and other cancer care providers. The majority of patients with HNSCC present with locoregionally advanced (LA) disease, for which combined modality treatment integrating chemotherapy and radiation therapy is often necessary to maximize tumor control. However, applying these approaches to an older population with concomitant comorbidities and higher risk for functional impairments remains challenging, and is exacerbated by the paucity of studies involving older adults. The purpose of this paper is to identify knowledge gaps in the evaluation and management of older adults with HNSCC and their caregivers, particularly those undergoing concurrent chemoradiation, through a review of the literature conducted by clinicians, researchers, and patient advocates. The findings highlight the importance of a geriatric assessment and the therapeutic paradigms and challenges relevant to this population. Furthermore, we identify the need for additional research and interventions related to key supportive care issues that arise during and after treatment in older adults with LA-HNSCC. Based on our findings, we prioritized these issues to guide future patient-oriented research endeavors to address these knowledge gaps and thus better serve this growing patient population.

show abstract

An Introduction to a Head and Neck Cancer-Specific Frailty Index and Its Clinical Implications in Elderly Patients: A Prospective Observational Study Focusing on Respiratory and Swallowing Functions

Cited by 39 publications

References 21 publications

Multicomponent Frailty Assessment Tools for Older People with Psychiatric Disorders: A Systematic Review

Multicomponent Frailty Assessment Tools for Older People with Psychiatric Disorders: A Systematic Review

Transoral laser microsurgery for glottic cancer in the elderly: Efficacy and safety

The Older Adult With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: Knowledge Gaps and Future Direction in Assessment and Treatment

Contact Info

Product

Resources

About