An Introduction to Biodiversity and Chemotaxonomy

Ramawat, K. G.

doi:10.1007/978-3-030-30746-2_1

Cited by 7 publications

(6 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The second-largest category of alkaloids after indole alkaloids is isoquinoline alkaloids [36] which are mainly derived from L-tyrosine and phenylalanine. In the 19th century, morphine was the first isoquinoline alkaloid isolated from Papaver somniferum [37].…”

Section: Isoquinoline and Related Alkaloids: A New Ray Of Hopementioning

confidence: 99%

“…Protoberberine alkaloids contain a tetracycline ring system and are mainly derived from the benzyltetrahydroisoquinoline by oxidation of the phenolic group and coupling with the N-methyl group of isoquinoline [36]. Natural protoberberine alkaloids have multiple pharmacological actions such as antiseptic, sedative, stomachic, analgesic action, and antiviral action [112].…”

Section: Protoberberine Alkaloidsmentioning

confidence: 99%

“…These type II isoquinoline alkaloids contain a three-ring system in which the B ring is reduced at C1-C2 and C3-C4. These alkaloids are the main precursor for the biosynthesis of many naturally occurring alkaloids including BBI, protoberberine, protopine, phthalideisoquinoline, and many others [36,128]. The chemical structures of several isoquinoline related alkaloids are given in Figure 5.…”

Section: Benzyltetrahydroisoquinoline and Benzylisoquinolinementioning

confidence: 99%

See 2 more Smart Citations

Bioactivity and In Silico Studies of Isoquinoline and Related Alkaloids as Promising Antiviral Agents: An Insight

Sharma

Manchanda

et al. 2022

Biomolecules

View full text Add to dashboard Cite

Viruses are widely recognized as the primary cause of infectious diseases around the world. The ongoing global pandemic due to the emergence of SARS-CoV-2 further added fuel to the fire. The development of therapeutics becomes very difficult as viruses can mutate their genome to become more complex and resistant. Medicinal plants and phytocompounds could be alternative options. Isoquinoline and their related alkaloids are naturally occurring compounds that interfere with multiple pathways including nuclear factor-κB, mitogen-activated protein kinase/extracellular-signal-regulated kinase, and inhibition of Ca2+-mediated fusion. These pathways play a crucial role in viral replication. Thus, the major goal of this study is to comprehend the function of various isoquinoline and related alkaloids in viral infections by examining their potential mechanisms of action, structure-activity relationships (SAR), in silico (particularly for SARS-CoV-2), in vitro and in vivo studies. The current advancements in isoquinoline and related alkaloids as discussed in the present review could facilitate an in-depth understanding of their role in the drug discovery process.

show abstract

Section: Isoquinoline and Related Alkaloids: A New Ray Of Hopementioning

confidence: 99%

Section: Protoberberine Alkaloidsmentioning

confidence: 99%

Section: Benzyltetrahydroisoquinoline and Benzylisoquinolinementioning

confidence: 99%

See 1 more Smart Citation

Bioactivity and In Silico Studies of Isoquinoline and Related Alkaloids as Promising Antiviral Agents: An Insight

Sharma

Manchanda

et al. 2022

Biomolecules

View full text Add to dashboard Cite

show abstract

“…These defensive secretions, or defense allomones, can constitute real molecular monsters due to their composition and sometimes 2 of 6 are only mono-component mixtures [17,18]. The components of millipede allomones, mostly benzoquinonoids, esters, cyanogenic compounds, alkaloids, hydrocarbons, and oxygenated derivatives with a molecular weight varying between 80 and 580 Da, are different for each order, class, and family of millipedes, with compositional differences related to environmental and eco-geographical conditions, inter-species interactions, type of feeding, age, sex, ontogenetic developmental phase etc., indicating some evolutionary patterns in interspecific or intraspecific differences, and that they may, therefore, be useful as chemotaxonomic biomarkers [19,20].…”

Section: Introductionmentioning

confidence: 99%

GC-MS Analysis of Defensive Secretions of a Cuban Endemic Millipede of the Genus Rhinocricus—Chemical Prospecting of Neotropical Biodiversity

Morales,

Villavicencio,

Cervantes

et al. 2023

Ecsoc 2023

View full text Add to dashboard Cite

show abstract

“…In addition to the genomic and morphological description, chemo-taxonomy, the characterization of species-specific metabolomes, has emerged as a complementary approach in species delineation 14 . A species and its metabolome are affected by environmental factors, being exposed to abiotic (pH, temperature, pressure, oxygen, light, salinity) and biotic factors (nutrients, presence/absence of predators) 15 .…”

Section: Introductionmentioning

confidence: 99%

From Persian Gulf to Indonesia: interrelated phylogeographic distance and chemistry within the genus Peronia (Onchidiidae, Gastropoda, Mollusca)

Maniei

Moghaddam

Crüsemann

et al. 2020

Sci Rep

View full text Add to dashboard Cite

the knowledge of relationships between taxa is essential to understand and explain the chemical diversity of the respective groups. Here, twelve individuals of the panpulmonate slug Peronia persiae from two localities in persian Gulf, and one animal of P. verruculata from Bangka island, indonesia, were analyzed in a phylogenetic and chemotaxonomic framework. Based on the ABGD test and haplotype networking using coi gene sequences of Peronia specimens, nine well-supported clades were found. Haplotype network analysis highlighted a considerable distance between the specimens of P. persiae and other clades. Metabolomic analysis of both species using tandem mass spectrometrybased GnpS molecular networking revealed a large chemical diversity within Peronia of different clades and localities. While P. persiae from different localities showed a highly similar metabolome, only few identical chemical features were found across the clades. the main common metabolites in both Peronia species were assigned as polypropionate esters of onchitriols and ilikonapyrones, and osmoprotectant amino acid-betaine compounds. On the other hand, the isoflavonoids genistein and daidzein were exclusively detected in P. persiae, while cholesterol and conjugated chenodeoxycholic acids were only found in P. verruculata. flavonoids, bile acids, and amino acid-betaine compounds were not reported before from onchidiidae, some are even new for panpulmonates. our chemical analyses indicate a close chemotaxonomic relation between phylogeographically distant Peronia species. Peronia Fleming, 1822, a panpulmonate slug genus, is typically distributed in tropical and subtropical regions of the Indo-Pacific ocean 1. The genus Peronia, with ten acknowledged species, has been reported from many localities ranging from the Indo-Pacific to the East Coast of Africa and to Hawaii 2-4. Due to undetected cryptic speciation, species diversity is often underestimated while the widespread distributions attributed to species is often overestimated 5. The integration of molecular and morphological methods has led to numerous discoveries of cryptic species complexes 6. This is also true for the genus Peronia, as was shown by Maniei et al. 3. To date, only three Peronia species are well investigated by molecular and/or morphology data, i.e.

show abstract

An Introduction to Biodiversity and Chemotaxonomy

Cited by 7 publications

References 41 publications

Bioactivity and In Silico Studies of Isoquinoline and Related Alkaloids as Promising Antiviral Agents: An Insight

Bioactivity and In Silico Studies of Isoquinoline and Related Alkaloids as Promising Antiviral Agents: An Insight

GC-MS Analysis of Defensive Secretions of a Cuban Endemic Millipede of the Genus Rhinocricus—Chemical Prospecting of Neotropical Biodiversity

From Persian Gulf to Indonesia: interrelated phylogeographic distance and chemistry within the genus Peronia (Onchidiidae, Gastropoda, Mollusca)

Contact Info

Product

Resources

About