An Introduction to Nanomedicine

Bhargava, Amber; Cheung, Janet; Eshaghian‐Wilner, Mary Mehrnoosh; Lee, Wan; Ravicz, Kodiak; Schlesinger, Mike; Shah, Yesha; Uppal, Abhishek

doi:10.1002/9781118993620.ch10

Cited by 2 publications

(3 citation statements)

References 35 publications

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“…Whereas early detection is highly involved in the efficient treatment of many brain diseases, such as brain cancer [93] and neurodegenerative disorders [94], the development of novel strategies for neuroimaging is crucial [93]. The interlink between nanotechnology and neuroscience, particularly neuroimaging, has shown a great potential in the field of nanomedicine [95], providing new possibilities for designing contrast agents and nanocarriers that target the brain [96].…”

Section: Nanotechnology-based Approaches For Neuroimagingmentioning

confidence: 99%

“…Nanotechnology-based materials, devices and electronic biosensors allow for enhanced visualization of brain tissue, resulting in greater spatial and temporal resolution and accuracy [95]. Furthermore, nanotechnology approaches improve the identification of biomarkers, the indicators for the biological state of disease, which is of key importance in early diagnosis [93]. Moreover, the blood-brain barrier restricts the permeation of conventional contrast agents that are used for neuroimaging as they are usually hydrophobic in nature and have a reduced half-time circulation.…”

Section: Nanotechnology-based Approaches For Neuroimagingmentioning

confidence: 99%

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Contrast Agents Delivery: An Up-to-Date Review of Nanodiagnostics in Neuroimaging

et al. 2019

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Neuroimaging is a highly important field of neuroscience, with direct implications for the early diagnosis and progression monitoring of brain-associated diseases. Neuroimaging techniques are categorized into structural, functional and molecular neuroimaging, each possessing advantages and disadvantages in terms of resolution, invasiveness, toxicity of contrast agents and costs. Nanotechnology-based approaches for neuroimaging mostly involve the development of nanocarriers for incorporating contrast agents or the use of nanomaterials as imaging agents. Inorganic and organic nanoparticles, liposomes, micelles, nanobodies and quantum dots are some of the most studied candidates for the delivery of contrast agents for neuroimaging. This paper focuses on describing the conventional modalities used for imaging and the applications of nanotechnology for developing novel strategies for neuroimaging. The aim is to highlight the roles of nanocarriers for enhancing and/or overcome the limitations associated with the most commonly utilized neuroimaging modalities. For future directions, several techniques that could benefit from the increased contrast induced by using imaging probes are presented.

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Section: Nanotechnology-based Approaches For Neuroimagingmentioning

confidence: 99%

Section: Nanotechnology-based Approaches For Neuroimagingmentioning

confidence: 99%

Contrast Agents Delivery: An Up-to-Date Review of Nanodiagnostics in Neuroimaging

et al. 2019

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“…2,3 Many different types of materials are used in dentistry and nanotechnology has signicant potential to improve their properties. 4 Several nanostructures can be utilized in dentistry, including nanobers, dendrimers, nanopores, nanoshells, nanorods, nanoparticles, dental nanorobots, nanorobotic dentifrice, nanosolutions, and nanoneedles. 2 Nanoparticles (NPs) are an excellent candidate for nanodentistry and can be made by ceramics, polymers, and metals.…”

Section: Introductionmentioning

confidence: 99%