In this paper, convergence results in a multivariate setting have been proved for a family of neural network operators of the maxproduct type. In particular, the coefficients expressed by Kantorovich type means allow to treat the theory in the general frame of the Orlicz spaces, which includes as particular case the L p -spaces. Examples of sigmoidal activation functions are discussed, for the above operators in different cases of Orlicz spaces. Finally, concrete applications to real world cases have been presented in both uni-variate and multivariate settings. In particular, the case of reconstruction and enhancement of biomedical (vascular) image has been discussed in details.2010 Mathematics Subject Classification. 41A25, 41A05, 41A30, 47A58.