An investigation into the kinematics of magnetically driven droplets on various (super)hydrophobic surfaces and their application to an automated multi-droplet platform

Agrawal, Prashant; Bachus, Kyle; Carriere, Gabrielle; Grouse, Phoenix; Oleschuk, Richard D.

doi:10.1007/s00216-018-1378-y

Cited by 5 publications

(4 citation statements)

References 40 publications

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“…The use of superhydrophobic surfaces, when combined with external forces (for example, gravity 91 and magnetism 92 , 93 ), allows droplets to be transported efficiently owing to the limited friction. A sequence of microdroplets in individual compartments with superhydrophobic coatings can be controllably transported in the same order using gravity with a simple rocking method 91 .…”

Section: Droplet Manipulationmentioning

confidence: 99%

Miniaturizing chemistry and biology using droplets in open systems

et al. 2023

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Open droplet microfluidic systems manipulate droplets on the picolitre-to-microlitre scale in an open environment. They combine the compartmentalization and control offered by traditional droplet-based microfluidics with the accessibility and ease-of-use of open microfluidics, bringing unique advantages to applications such as combinatorial reactions, droplet analysis and cell culture. Open systems provide direct access to droplets and allow on-demand droplet manipulation within the system without needing pumps or tubes, which makes the systems accessible to biologists without sophisticated setups. Furthermore, these systems can be produced with simple manufacturing and assembly steps that allow for manufacturing at scale and the translation of the method into clinical research. This Review introduces the different types of open droplet microfluidic system, presents the physical concepts leveraged by these systems and highlights key applications.

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Section: Droplet Manipulationmentioning

confidence: 99%

Miniaturizing chemistry and biology using droplets in open systems

et al. 2023

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“…The optimized platforms were applied in a quantitative fluorescence-based DNA assay under 2 min. 91 2.3 Magnetic force and chemical interaction 2.3.1 Dynamic force measurements. The force measurement of a single chemical interaction succeeded for DNA by applying a pulling force using a magnetic bead in 1992 by Finzi et al 92 Individual λ-DNA (48.5 kbp) molecules were chemically attached by one of their ends to a glass slide and by their other end to a magnetic bead of 2.9 μm in diameter.…”

Section: Magnetophoresismentioning

confidence: 99%

Applications of magnetic and electromagnetic forces in micro-analytical systems

2023

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“…13,14 This technique allows for the manipulation and transport of droplets without the need for microfluidic channels or devices. DMSS offers several advantages over traditional liquid pipetting techniques, including reduced dead volume and sample loss due to the reduced surface interactions, precise control over droplet size and composition, miniaturization and high-throughput capabilities for high-throughput screening of large numbers of samples, and versatility for a wide range of applications, including droplet-based assays, [15][16][17] containerless microreaction, 18,19 and so on. These advantages make DMSS a promising technology for a wide range of applications in fields such as biology, chemistry, and materials science.…”

Section: Introductionmentioning

confidence: 99%