An investigation into the psychobiology of social phobia: personality domains and serotonergic function

Chatterjee, Seshadri Sekhar; Sunitha, T.; Velayudhan, A.; Khanna, Sumant

doi:10.1111/j.1600-0447.1997.tb10144.x

Cited by 60 publications

(41 citation statements)

References 33 publications

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“…The present findings converge with those previously reported using the KSP, where high scores on anxiety scales were associated with social phobia (7), as well as with those using the revised NEO Personality Inventory, where high neuroticism and low extraversion were revealed in social phobics (30). Also, the present results are largely in accordance with those reported previously for TCI personality dimensions in social phobia (22). The only differences between the studies is that Chatterjee et al (22) noted lower Novelty seeking in social phobics but not lower Persistence, as was found in our investigation.…”

Section: Discussionsupporting

confidence: 95%

“…Also, the present results are largely in accordance with those reported previously for TCI personality dimensions in social phobia (22). The only differences between the studies is that Chatterjee et al (22) noted lower Novelty seeking in social phobics but not lower Persistence, as was found in our investigation. This inconsistency may be due to the high Axis I comorbidity (75%) in the former study.…”

Section: Discussionsupporting

confidence: 95%

“…Higher scores on the scales for inhibition of aggression and psychic anxiety were the only significant measures that distinguished social phobics with and without comorbid avoidant personality disorder. The presence of maladaptive personality traits in social phobia has also been demonstrated by application of the Temperament and Character Inventory (TCI), where high levels of harm avoidance and low levels of Novelty seeking, Self-directness and Cooperativeness were shown in 20 individuals with social phobia (22).…”

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confidence: 97%

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Personality dimensions measured by the Temperament and Character Inventory (TCI) in subjects with social phobia

Marteinsdóttir

Tillfors²,

Furmark³

et al. 2003

Nordic Journal of Psychiatry

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The present study investigated personality dimensions by means of the Temperament and Character Inventory (TCI) in subjects with social phobia with or without a co-existing avoidant personality disorder. Thirty-one individuals with social phobia were recruited through advertisement and diagnosed with the Structured Clinical Interview for DSM-IV I and II psychiatric disorders. Comorbid Axis I psychiatric disorders were diagnosed in 29% of the cases. Co-occurring personality disorders were present in 55.8% of the cases, and avoidant personality disorder in 48.4%. The social phobia subjects, as compared to healthy controls of the same age, scored significantly higher in the TCI dimension measuring Harm avoidance but significantly lower in Persistence, Self-directedness, Cooperativeness and Self-transcendence. Presence of avoidant personality disorders in the social phobia subjects was associated with significantly higher Harm avoidance, particularly on the subscale Shyness with strangers. In conclusion, individuals with social phobia were characterized by high comorbidity of avoidant personality disorder and deviations in TCI personality dimensions. Enhanced Harm avoidance was the most prominent personality trait. The observed deviations in TCI dimensions were primarily related to the social phobia itself and not to the presence of concurrent personality disorders.

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Section: Discussionsupporting

confidence: 95%

Section: Discussionsupporting

confidence: 95%

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confidence: 97%

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Personality dimensions measured by the Temperament and Character Inventory (TCI) in subjects with social phobia

Marteinsdóttir

Tillfors²,

Furmark³

et al. 2003

Nordic Journal of Psychiatry

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“…The vertical lines represent the overall result of meta-analysis. Names of first authors refer to the following references: Mertol [30], Mula [31], Wachleski [32], Marchesi [33], Battaglia [37], Wiborg [35], Cowley [40], Saviotti [41], Mörtberg [45], Lochner [46], Marteinsdottir [49], Pelissolo [50], Kim (1996) [51], Chatterjee [52], Faytout [47], Kim (2009) [53], Alonso [57], Cruz-Fuentes [58], Lyoo [59], Kusunoki [61], Richter [62], Pfohl [63], Ettelt [56]. …”

Section: Resultsmentioning

confidence: 99%

Meta-Analysis of Anxiety Disorders and Temperament

et al. 2014

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Background: The aims of the present study were to explore whether symptoms in different anxiety disorders are associated with Cloninger's model temperament dimensions novelty seeking (NS), harm avoidance (HA), reward dependence and persistence compared with control subjects in clinical samples of adults or late adolescents. Method: Literature search in the following databases: Cochrane Library, PubMed (Medline), Web of Science, Psycinfo and PsycArticles. Systematic review, grading the level of evidence and meta-analysis for each disorder by comparing the temperament dimension scores between patient and control samples in single studies. Results: A total of 40 papers fulfilled the inclusion criteria. Meta-analyses were conducted on a total of 24 studies focusing on panic disorder (PD), social anxiety disorder (SAD) and obsessive-compulsive disorder (OCD). The primary finding was a constant and clinically marked positive association between the HA temperament dimension and symptoms of PD, SAD and OCD, with a most marked effect in SAD, and a moderate effect in OCD and PD. Second, less marked and clinically marginal associations between NS score and SAD and OCD (negative associations), but no associations with PD were observed. The meta-analyses revealed heterogeneity between the results of individual studies, especially in the analyses including SAD and OCD. Conclusions: PD, SAD and OCD share a marked and state-dependent avoidant behavioral pattern, which is common for all anxiety disorders. However, PD showed a different pattern of arousal to novel stimuli from that of SAD and OCD. The findings are state dependent and based on cross-sectional studies.

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“…The 100-item Tridimensional Personality Questionnaire (TPQ; Cloninger, 1987a,b) was designed to measure harm avoidance and two other personality traits-novelty seeing and reward dependence. Several studies have reported greater harm avoidance in individuals with SAD when compared to controls (Chatterjee, Sunitha, Velayudhan, & Khanna, 1997;Marteinsdottir, Tillfors, Furmark, Anderberg, & Ekselius, 2003;.…”

Section: Introductionmentioning

confidence: 99%

Sensory-processing sensitivity in social anxiety disorder: Relationship to harm avoidance and diagnostic subtypes

Hofmann

Bitran

2007

Journal of Anxiety Disorders

138

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Sensory-processing sensitivity is assumed to be a heritable vulnerability factor for shyness. The present study is the first to examine sensory-processing sensitivity among individuals with social anxiety disorder. The results showed that the construct is separate from social anxiety, but it is highly correlated with harm avoidance and agoraphobic avoidance. Individuals with a generalized subtype of social anxiety disorder reported higher levels of sensory-processing sensitivity than individuals with a non-generalized subtype. These preliminary findings suggest that sensory-processing sensitivity is uniquely associated with the generalized subtype of social anxiety disorder.Recommendations for future research are discussed.

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An investigation into the psychobiology of social phobia: personality domains and serotonergic function

Cited by 60 publications

References 33 publications

Personality dimensions measured by the Temperament and Character Inventory (TCI) in subjects with social phobia

Personality dimensions measured by the Temperament and Character Inventory (TCI) in subjects with social phobia

Meta-Analysis of Anxiety Disorders and Temperament

Sensory-processing sensitivity in social anxiety disorder: Relationship to harm avoidance and diagnostic subtypes

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