An Investigation into the Recent Increase in Gastric Cancer in the USA

Balakrishnan, Maya; George, Rollin; Sharma, Ashish; Graham, David Y.; Malaty, Hoda M.

doi:10.1007/s10620-018-5012-9

Cited by 12 publications

(19 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results are compelling as there is a lack of research regarding GC trends in the US. 9,25,26 Interestingly, our results show a deviation from previous trends of declining cases of GC overall. Balakrishnan and colleagues reported a significant increase among Hispanics while non-Hispanic Whites’ and Blacks’ incidence remained stable.…”

Section: Discussioncontrasting

confidence: 95%

Age-Based Trends of Gastric Adenocarcinoma in the United States

Trumbull

Lemini

Elli

et al. 2020

The American Surgeon™

View full text Add to dashboard Cite

Background Recent studies have shown an increase in the incidence of gastric cancer (GC) among young adults in Asia and Latin America. However, it is unknown if a similar trend is happening in the United States (US). Methods A retrospective review of the National Cancer Data Base was conducted to identify patients diagnosed with gastric adenocarcinoma between the years of 2004 and 2013. Results A total of 93 734 patients were included. The 2 age groups below 40 did not see a change in GC incidence; however, age groups above 40 had increasing incidence. Patients aged 18-25 had the largest proportion of stage 4 disease and a poor survival (median 11.5 months), compared to older patients. Conclusion Despite the increasing trend of GC among individuals, the incidence of GC among young adults is not increasing. However, this subpopulation presents at more advanced stages (clinical stage 4) and thus has worse survival.

show abstract

Section: Discussioncontrasting

confidence: 95%

Age-Based Trends of Gastric Adenocarcinoma in the United States

Trumbull

Lemini

Elli

et al. 2020

The American Surgeon™

View full text Add to dashboard Cite

show abstract

“…There are some characteristics of these new cases of non-cardia cancer in young individuals that are different from the traditional non-cardia cancer of all individuals. There is a concordance in most of the reports that young subjects (<40 years) with non-cardia cancer had a more diffuse type than older subjects (>40 years) [ 46 , 47 , 48 , 49 ]. Furthermore, contrary to previous statistics in which gastric cancer affected males twice as frequently as females [ 48 ], non-cardia cancer in young subjects (<40 years) had an occurrence in women that was higher than or equal to that in men [ 46 , 47 , 48 ].…”

Section: Gastric Microbiota and Its Influence On Gastric Carcinogesupporting

confidence: 72%

“…A possible explanation for the recent increase in gastric cancer in the USA is perhaps the large immigration of Hispanic populations that has occurred recently [ 49 ]. However, the incidence of gastric cancer in Hispanics cannot explain the increased incidence of gastric cancer in young individuals in all regions of the world.…”

Section: Gastric Microbiota and Its Influence On Gastric Carcinogementioning

confidence: 99%

Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer?

Perez

2018

IJMS

View full text Add to dashboard Cite

Helicobacter pylori is the most abundant bacterium in the gastric epithelium, and its presence has been associated with the risk of developing gastric cancer. As of 15 years ago, no other bacteria were associated with gastric epithelial colonization; but thanks to new methodologies, many other non-H. pylori bacteria have been identified. It is possible that non-H. pylori may have a significant role in the development of gastric cancer. Here, we discuss the specific role of H. pylori as a potential trigger for events that may be conducive to gastric cancer, and consider whether or not the rest of the gastric microbiota represent an additional risk in the development of this disease.

show abstract

“…These findings support burgeoning evidence from numerous studies that have shown differential effects of immigration status on health and mortality (Flores et al, 2018;John, Phipps, Davis, & Koo, 2005;Keegan et al, 2010;Pinheiro, Callahan, Stern & de Vries, 2018;Pinheiro et al, 2009;Stern et al, 2016). There is substantial evidence that among Hispanic women, those of U.S. birth have a higher breast cancer incidence than immigrants (U.S. born vs. foreign-born) (Balakrishnan, George, Sharma, Graham, & Malaty, 2018;Heck et al, 2016;John et al, 2005;Keegan et al, 2010;Pike et al, 2002;Pinheiro et al, 2009;Thomas & Karagas, 1996). Multiple studies have also shown that breast cancer risk is higher among immigrants who migrate at younger ages (Balzi et al, 1993;Bernstein, Flannery & Reynolds, 1993;John et al, 2005;Mousavi, Fallah, Sundquist, & Hemminki, 2012;Shimizu et al, 1991).…”

Section: Life Course Stage At Immigrationsupporting

confidence: 68%

Hereditary Breast Cancer Risk Analysis in Uninsured Mexican-Origin Women Living in the U.S.–Mexico Border Region

Salinas

Roy

Dwivedi

et al. 2019

Hisp Health Care Int

View full text Add to dashboard Cite

Purpose: This article describes the risk of hereditary breast cancer (HBC) in low-income Hispanic women living on the U.S.–Mexico border using the Pedigree Assessment Tool (PAT). Method: The PAT was administered as part of the El Paso and Hudspeth County Breast Cancer Education, Screening and NavigaTion program (BEST). Baseline data ( n = 1,966) from this program was used to analyze risk factors for HBC. Analysis was conducted to determine significant covariates associated with the presence of any PAT risk factors. Results: The PAT identified 17% (95% CI [15%, 19%]) of the women in the study as having some risk of HBC. Having had a mammogram within 3 years was significantly associated with having any PAT risk factors (odds ratio [OR] = 1.79, p = .006). Women who immigrated to the United States during childbearing age (OR = 0.610, p = .009) or during peri/menopause (OR = 0.637, p = .024) were significantly less likely to have any PAT risk factors. Discussion: The PAT instrument detected a substantial pool of women who may be at risk for HBC. A significant proportion of these women were not up to date mammogram. Conclusions: The PAT is an effective tool to identify women at risk for HBC and encourage regular screening.

show abstract

An Investigation into the Recent Increase in Gastric Cancer in the USA

Cited by 12 publications

References 24 publications

Age-Based Trends of Gastric Adenocarcinoma in the United States

Age-Based Trends of Gastric Adenocarcinoma in the United States

Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer?

Hereditary Breast Cancer Risk Analysis in Uninsured Mexican-Origin Women Living in the U.S.–Mexico Border Region

Contact Info

Product

Resources

About