An investigation of 2 techniques for optimizing joint surface congruency using multiple cylindrical osteochondral autografts

Pearce, Simon G.; Hurtig, Mark; Clarnette, Richard; Kalra, Manpreet; Cowan, Bryce J.; Miniaci, Anthony

doi:10.1053/jars.2001.19966

Cited by 153 publications

(118 citation statements)

References 18 publications

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“…Intrinsic stability has been shown to be an important factor for optimal in-growth of the transplanted plugs (Pearce et al 2001, Makino et al 2002) and thus appears to be correlated with a successful outcome. It seems plausible that the longer the plugs the greater the stability-because of higher frictional forces that hold the plugs in place.…”

mentioning

confidence: 99%

Press-fit stability of an osteochondral autograft: Influence of different plug length and perfect depth alignment

et al. 2006

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Background Osteochondral autologous transplantation is used for the treatment of full-thickness articular cartilage lesions of a joint. Press-fit stability is an important factor for good survival of the transplanted plugs.Material and methods 36 plugs of three different lengths were transplanted in fresh-frozen human knees. On one condyle, 3 plugs were exactly matched to the depth of the recipient site ("bottomed" plugs) and on the opposite condyle 3 plugs were 5 mm shorter than the depth of the recipient site ("unbottomed" plugs). Plugs were left protruding and then pushed in until flush, and then to 2 mm below flush level, using a loading apparatus.Results Longer plugs needed higher forces to begin displacement. At flush level, bottomed plugs needed significantly higher forces than unbottomed plugs to become displaced below flush level (mean forces of 404 N and 131 N, respectively). Shorter bottomed plugs required higher forces than longer bottomed ones.Interpretation Bottomed plugs generally provide much more stability than unbottomed ones. Short bottomed plugs are more stable than long bottomed plugs. Thus, in clinical practice it is advisable to use short bottomed plugs. If, however, unbottomed plugs are still chosen, the longer the plug the higher the resulting stability will be because of higher frictional forces.

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mentioning

confidence: 99%

Press-fit stability of an osteochondral autograft: Influence of different plug length and perfect depth alignment

et al. 2006

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“…A lot of basic research in articular cartilage repair has been conducted [16,21,22] . The purpose of this study was to evaluate and compare three options when restoring osteochondral defects with OATS (mosaicplasty) in a rabbit model.…”

Section: Discussionmentioning

confidence: 99%

Donor’s site evaluation after restoration with autografts or synthetic plugs in rabbits

Intzoglou

Mastrokalos

Korres

et al. 2014

WJO

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AIM:To investigate donor site's area histological and immunohistochemical knee cartilage appearances after resurfacing iatrogenic defects with biosynthetic plugs orautografts. METHODS:Thirty New Zealand White rabbits were used in this study. A full-thickness cylindrical defect of 4.5 mm (diameter) × 7 mm (depth) was created with a hand drill in the femoral groove of every animal. In Group A (n = 10) the defect of the donor site was repaired with a biosynthetic osteochondral plug, in Group B (n = 10) with an osteochondral autograft, while in Group C (control group of 10) rabbits were left untreated. RESULTS:Twenty-four weeks postoperatively, smooth articular cartilage was found macroscopically in some trocleas' surfaces; in all others, an articular surface with discontinuities was observed. Twenty-eight out of 30 animals were found with predominantly viable chondrocytes leaving the remaining two -which were found only in the control group-with partially viable chondrocytes. However, histology revealed many statistical differences between the groups as far as the International Cartilage Repair Society (ICRS) categories are concerned. Immunofluoresence also revealed the presence of collagen Ⅱ in all specimens of Group B, whereas in Group A collagen Ⅱ was found in less specimens. In Group C collagen Ⅱwas not found. CONCLUSION:The matrix, cell distribution, subchondral bone and cartilage mineralization ICRS categories showed statistically differences between the three groups. Group A was second, while group B received the best scores; the control group got the worst ICRS scores in these categories. So, the donor site area, when repairing osteochondral lesions with autografting systems, is better amended with osteochondral autograft rather than bone graft substitute implant.

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“…In an animal study [4], plugs that were too high were found to subside under weight bearing but showed fissuring, bone cysts, and poor bony incorporation. Elevated angled grafts (with an angled tip of the plug surface above the surrounding surface) are subject to increased contact pressure [5] which leads to peak loading and abrasion of the plug's surface [10].…”

Section: Related Workmentioning

confidence: 99%

“…Plugs that are too high can result in poor plug integration due to micromotion and increased contact pressure [4,5]. Plugs that are too low can result in cartilage necrosis and fibrocartilage overgrowth [6].…”

Section: Introductionmentioning

confidence: 99%

Automated Planning of Computer Assisted Mosaic Arthroplasty

Inoue

Kunz

Hurtig

et al. 2011

Lecture Notes in Computer Science

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Abstract. We describe and evaluate a computer algorithm that automatically develops a surgical plan for computer assisted mosaic arthroplasty, a technically demanding procedure in which a set of osteochondral plugs are transplanted from a non-load-bearing area of the joint to the site of a cartilage defect. We found that the algorithm produced plans that were at least as good as a human expert, had less variability, and took less time.

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An investigation of 2 techniques for optimizing joint surface congruency using multiple cylindrical osteochondral autografts

Cited by 153 publications

References 18 publications

Press-fit stability of an osteochondral autograft: Influence of different plug length and perfect depth alignment

Press-fit stability of an osteochondral autograft: Influence of different plug length and perfect depth alignment

Donor’s site evaluation after restoration with autografts or synthetic plugs in rabbits

Automated Planning of Computer Assisted Mosaic Arthroplasty

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