“…Being an adaptive, self-learning and self-organizing system, ANN is able to identify complex non-linear relationships between variables [ 35 ]. Moreover, BPNN has already proven its usefulness regarding several psychiatric and psychosomatic investigations in the past [ 36 , 37 , 38 , 39 , 40 , 41 ]. Overall, BPNN is better suited to determine individual prediction accuracy, and thus, might help increase the uptake of PO [ 42 ].…”