A wideband microstrip open-slot antenna with dual-frequency dual-sense circular polarization (CP) is presented in this paper. A bent feeding structure and three radiating slots, including a modified cross-shaped, an inverted F-shaped, and an inverted L-shaped slots, are designed to excite two orthogonal electric fields with a quadrature phase difference for a radiating right-hand circularly polarized (RHCP) wave at 2.5 GHz and left-hand circularly polarized (LHCP) wave at 3.3 GHz. To improve the axial-ratio (AR), a bent parasitic element is introduced near the microstrip line. Multiple resonances are merged to achieve a large bandwidth of 2620 MHz (104.8%) from 2.2 GHz to 4.82 GHz. The measured AR bandwidths are 460 MHz (18.4%) at the lower band (2.5 GHz) and 2150 MHz (65.1%) at the upper band (3.3 GHz).