An investigation of the correlation between blood concentration of mizoribine and its efficacy in treatment of rheumatoid arthritis based on indices of drug survival and improvement in DAS28-CRP

Ohtsubo, Hideo; Ohkura, Sanae; Akimoto, Masaki; Arishima, Yoshiya; Sunahara, Nobuhiko; Izumihara, Tomomaro; Eiraku, Nobutaka; Yoshitama, Tamami; Matsuda, Takemasa

doi:10.3109/s10165-012-0611-3

Modern Rheumatology

2012

DOI: 10.3109/s10165-012-0611-3

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An investigation of the correlation between blood concentration of mizoribine and its efficacy in treatment of rheumatoid arthritis based on indices of drug survival and improvement in DAS28-CRP

Hideo Ohtsubo¹,

Sanae Ohkura²,

Masaki Akimoto³

et al.

Abstract: The results of the present study indicate that it is possible to increase the efficacy of MZR in a blood concentration-dependent manner, and also to control RA over a prolonged period, using single administration of MZR on alternate days at an increased dose.

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An investigation of the correlation between blood concentration of mizoribine and its efficacy in treatment of rheumatoid arthritis based on indices of drug survival and improvement in DAS28-CRP

Abstract: The results of the present study indicate that it is possible to increase the efficacy of MZR in a blood concentration-dependent manner, and also to control RA over a prolonged period, using single administration of MZR on alternate days at an increased dose.

Cited by 0 publications

References 10 publications

No citations

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