Abstract:The aim of this study was to examine the effects of the sitting posture on the lower limb venous flow and to explore the beneficial effects of neuromuscular electrical stimulation (NMES) and an ottoman-type seat on the venous flow. Healthy adult volunteers without a history of lower limb surgery or thromboembolism were recruited, and the flow velocity, cross-sectional area, and flow volume of the popliteal vein were measured using Doppler ultrasound. A posture change from the prone position to the sitting position on the ottoman-type seat decreased the flow velocity and increased the cross-sectional area of the popliteal vein, and the flow volume was not altered over 120 min. The flow velocity was further decreased, and the crosssectional area was further increased by subjects sitting on a regular driving seat when compared with the values obtained with an ottoman-type seat. The popliteal flow velocity in the NMES leg was significantly higher than in the non-NMES leg throughout the 120-min testing in the sitting position, but no difference in the cross-sectional area was found between the NMES and the non-NMES legs. Thus lower limb venous stasis elicited by the sitting posture was improved by the ottoman-type seat and NMES.Key words: muscle contraction, electrical stimulation, blood flow.Scurr et al. [1] reported that after long-haul air travel, symptomless deep venous thrombosis (DVT) develops in 10% of passengers, which is a surprisingly large proportion. The sitting posture in an airplane exposes passengers to the combined effects of movement restriction and gravitational pressure gradient between the heart and the lower limbs; this might enhance venous pooling/stasis, thereby increasing the chances of the development of DVT. Accordingly, the effects of sitting posture on lower limb hemodynamics have been a matter of great interest, and it was found that the venous flow velocity in the lower limbs was decreased and the diameter of the popliteal vein was increased by a sitting posture [2][3][4][5]. Devices that increase the venous flow velocity are thought to be effective in reducing venous stasis, and many techniques, including neuromuscular electrical stimulation (NMES) [6][7][8], have been proposed for increasing venous flow velocity. The metabolic demands of exercising skeletal muscles are met by increasing their blood flow, thereby supplying additional oxygen; this is a well-known phenomenon. This is also true in the case of passive electrical stimulation [9,10]. Furthermore, venous flow velocity increases in response to muscle contraction, and the increased velocity contributes to venous expulsion [10]. NMES increases the venous flow velocity in a stimulation-dependent manner, and the effect lasts for 4 h [7]. However, the extent to which NMES can improve the suppression of venous flow induced by a sitting posture remains unclear. To examine this, the popliteal venous flow velocity was measured consecutively in the horizontal prone position and then in the sitting position in both NMES and non-N...