An investigation of the effects of &amp;lt;i&amp;gt;BMPR1B&amp;lt;/i&amp;gt;, &amp;lt;i&amp;gt;BMP15&amp;lt;/i&amp;gt;, and &amp;lt;i&amp;gt;GDF9&amp;lt;/i&amp;gt; genes on litter size in Ramlıç and Dağlıç sheep

Çelikeloğlu, Koray; Tekerli, Mustafa; Erdoğan, Metin; Koçak, Serdar; Hacan, Özlem; Bozkurt, Zehra

doi:10.5194/aab-64-223-2021

Cited by 8 publications

(4 citation statements)

References 24 publications

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“…Texel is one of the most known muscled sheep breeds. The single nucleotide polymorphism (g+6723G > A) found in the 3 UTR region of GDF8 gene in Texel sheep which is known as myostatin was reported to cause superior muscularity (Clop et al, 2006;Çelikeloglu et al, 2021;Grasset et al, 2009;Johnson et al, 2005;Yalçın et al, 1978;Yayvan and Özkul, 2018). This mutation accelerates growth and increases muscularity in Texel and does not have a negative effect on the eating quality and intramuscular fat of the loin (Kijas et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

The comparative results of myostatin introgression from donor Texel to recipient Ramlıç sheep with the aspects of growth, pre-, and post-slaughter carcass traits in the second backcross generation

et al. 2022

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Abstract. The aim of the study was to evaluate the growth, body and ultrasonic measurements and some carcass traits of purebred Ramlıç, Texel and crossbred (87.5 % Ramlıç and 12.5 % Texel) lambs in a marker-assisted introgression (MAI) project. The effects of some environmental factors such as genotype, sex, birth type, dam age, weaning age, and birth weight on growth, ultrasound measurements, and carcass traits were significant (P<0.05). There were no significant differences between pure Ramlıç and its myostatin carrier (+/-) and non-carrier (-/-) second backcrosses (BC2) for birth weight, daily live weight gain, and weaning weight. The BC2 genotype (+/-) was statistically caught up with pure Ramlıç for wither height, body length, and rump width. Differences in the longissimus muscle depth indicated that the BC2 (+/-) genotypes tended to be better for both pure Ramlıç and Texel lambs. Texel lambs were superior to Ramlıç in the aspect of some carcass characteristics such as leg length, cold right-half carcass weight, foreleg weight in the left-half carcass, and muscle weight in the left leg. BC2 (+/-) lambs were in the middle of both breeds for the traits. BC2 lambs carrying myostatin did not vary from Ramlıç morphologically. The new type of Ramlıç was also closer to Texel in the aspect of carcass characteristics. In this connection, improvement of indigenous breeds could be achieved by MAI without changing the essential characteristics. For the summary, please visit http://www.mustafatekerli.com (last access: 14 June 2022).

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Section: Introductionmentioning

confidence: 99%

The comparative results of myostatin introgression from donor Texel to recipient Ramlıç sheep with the aspects of growth, pre-, and post-slaughter carcass traits in the second backcross generation

et al. 2022

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“…As a candidate gene, BMP15 were well documented in the world for sheep fecundity. In general, the interest in fecundity gene research has been more on sheep in Türkiye, as is the case all over the world (Hanrahan et al, 2004;Wang et al, 2015;Çelikeloğlu et al, 2021;Kırıkçı, 2023a;Kırıkçı, 2023b). The main reason for this may be the consumption of more sheep meat within small ruminants.…”

Section: Discussionmentioning

confidence: 99%

Genetic Screening of FecXG Polymorphism in Saanen Goat (Capra hircus) Breed in Türkiye

AĞYAR,

KIRIKÇI

2024

Black Sea Journal of Agriculture

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Determination of fecundity gene mutations and utilizing them in breeding programs offers the opportunity to improve productivity. The BMP15/FecX gene is one of the candidate genes with significant effects on multiple births in sheep. Many studies demonstrated that BMP15 gene mutations increase the rate of multiple births in small ruminants. Despite numerous studies on fecundity genes in sheep in Turkey, there is almost no comparable study in goats. Therefore, the objective of the current study was to investigate FecXG mutation in the exon 2 region of BMP15 gene in Saanen goats (Capra hircus). A total of 24 samples were used to investigate the FecXG mutation in Saanen goats raised in the Muş Plain of Turkey. A fragment of 141 bp of BMP15 gene was amplified by PCR and then products subjected to the digestion of restriction enzyme HinfI. The results of this preliminary study showed that the examined Saanen goats did not have a FecXG mutation.

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“…For example, many studies have shown that BMPR1B is associated with litter size in animals [32][33][34]. It is the main gene that affects the ovulation rate and litter size in sheep [35][36][37]. In addition, a series of studies have confirmed that the BMPR1B can affect follicular development, ovulation [38], and cause ovarian insufficiency [39].…”

Section: Discussionmentioning

confidence: 99%

Genome-Wide Selective Analysis of Boer Goat to Investigate the Dynamic Heredity Evolution under Different Stages

Yuan

Zhang

Liu

et al. 2022

Animals

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Boer goats, as kemp in meat-type goats, are selected and bred from African indigenous goats under a long period of artificial selection. Their advantages in multiple economic traits, particularly their plump growth, have attracted worldwide attention. The current study displayed the genome-wide selection signature analyses of South African indigenous goat (AF), African Boer (BH), and Australian Boer (AS) to investigate the hereditary basis of artificial selection in different stages. Four methods (principal component analysis, nucleotide diversity, linkage disequilibrium decay, and neighbor-joining tree) implied the genomic diversity changes with different artificial selection intensities in Boer goats. In addition, the θπ, FST, and XP-CLR methods were used to search for the candidate signatures of positive selection in Boer goats. Consequently, 339 (BH vs. AF) and 295 (AS vs. BH) candidate genes were obtained from SNP data. Especially, 10 genes (e.g., BMPR1B, DNER, ITGAL, and KIT) under selection in both groups were identified. Functional annotation analysis revealed that these genes are potentially responsible for reproduction, metabolism, growth, and development. This study used genome-wide sequencing data to identify inheritance by artificial selection. The results of the current study are valuable for future molecular-assisted breeding and genetic improvement of goats.

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An investigation of the effects of <i>BMPR1B</i>, <i>BMP15</i>, and <i>GDF9</i> genes on litter size in Ramlıç and Dağlıç sheep

Cited by 8 publications

References 24 publications

The comparative results of myostatin introgression from donor Texel to recipient Ramlıç sheep with the aspects of growth, pre-, and post-slaughter carcass traits in the second backcross generation

The comparative results of myostatin introgression from donor Texel to recipient Ramlıç sheep with the aspects of growth, pre-, and post-slaughter carcass traits in the second backcross generation

Genetic Screening of FecXG Polymorphism in Saanen Goat (Capra hircus) Breed in Türkiye

Genome-Wide Selective Analysis of Boer Goat to Investigate the Dynamic Heredity Evolution under Different Stages

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