An investigation of the pyrolysis of oligopeptides by Curie-point pyrolysis—tandem mass spectrometry

Thermal characterization of new, artificially aged and historical leather and parchment

“…DKPs are cyclic dipeptides formed from the amino acid residues of the samples during pyrolysis. The formation mechanisms of these compounds were discussed in detail by Voorhees et al [17] and Fabbri et al [18]. Proline-glycine DKP (pro-gly, peak #40) is the most abundant among all, in accordance with the fact that glycine and proline are the major constituents of collagen.…”

“…They exposed the materials to high concentrations of chemical pollutants (SO 2 and NO x ) and observed that the DSC peak was shifted to lower temperature with the aging time and became smaller and broader. It was also reported applying pyrolysis-mass spectrometry (Py-MS) [17] that the major pyrolysis products of peptides and proteins are 2,5-diketopiperazines, which are cyclic dimers of amino acids. Fabbri and coworkers [18] studied the formation of 2,5-diketopiperazines during the pyrolysis of linear dipeptides, tripeptides and proteins (e.g., collagen) using pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) system.…”

Evaluate the pyrolysis pathway of glycine and glycylglycine by TG–FTIR

“…And the decomposition of dipeptide and polypeptides at high temperature will also produce DKP. It has been suggested that one of the main primary pyrolysis reactions is the formation of DKP in the pyrolysis of oligopeptides, polypeptides and protein [1,[28][29][30]. Then that the reaction of cracking of DKP took place at high temperature, 400-800 8C, can be understood.…”

The chemistry of soil organic nitrogen: a review

“…Pyrazines are also formed by the thermal degradation of dipeptides (alanyl serine and glycyl serine) (Merrit and Robertson 1967) and polypeptides (Martin et al 1979). Interestingly, Curie-point tandem mass spectrometry of oligopeptides gave diketopiperazines or cyclic dipeptides as major decomposition products and allowed to identify peptide pairs present in complex systems (Voorhees et al 1994).…”