Quality of life refers to the convenience and satisfaction of individuals' living conditions. Most of the researches on the quality of life has been done in the medical, psychological, and social fields. Evaluation of the quality of life by university academic staff is the aim of this study. In this research, quality of life perceptions was tried to be measured with the application made in Urmia and Van Yuzuncu Yil universities. The main question of the research is to examine the status of quality of life and determine the age, marriage, etc. to compare contextual variables with quality of life. This research was carried out with the descriptive-analytical method and was performed with the survey method. As a data collection method, the World Health Organization's quality of life scale was used. The statistical population of this research is all academic staff of Van Yuzuncu Yil and Urmia universities. Its sampling is 335 academic staff, reached by stratified random sampling method, which is a proportional allocation type based on Cochran's formula. As a result of examining the quality of life and physical, social, environmental, mental, and general quality components among the academicians of Urmia and Van Yuzuncu Yil Universities, it was observed that the physical health status of the Urmia University faculty members had a higher average. When the social health status of the participants were compared, it was shown that the social health score averages of the faculty members of Van Yuzuncu Yil University were higher than the average scores of the faculty members of Urmia University. As a result of environmental health and public health analysis; the average of the faculty members of Van Yuzuncu Yil University is higher. In line with these results, it has been evaluated that factors such as economic benefits, environmental conditions, and social life increase the quality of life more. The study was completed by writing the conclusion part and making various suggestions.