An ion-gate response of the cysteine-containing dipeptide monolayers formed on a gold electrode. The effects of alkaline earth ions

Elucidation of the electron transfer mechanism of marker ions at SAMs with charged head groups

“…It was also shown that both marker ions (and we believe: probably all highly charged marker ions) bind efficiently to oppositely charged electrode surfaces. Moreover, it has been reported that micromolar concentrations of highly charged non-electroactive [3,7,12,16,18] and electroactive species [9] which bind to charged SAM surfaces can either enhance or suppress the marker ion current. This type of signal amplification or suppression has been called ion-gate or ion-channel sensing and has been used for electroanalytical applications.…”

“…Generally, all of these represent thin layers of less than one to a few nanometers thickness. Correspondingly the analyte species were originally highly charged inorganic ions and protons [7,10,16,19], and later, specific membrane interaction partners [20], molecular guests [11], protein interaction partners [15,21], and single stranded DNA probes [17]. Thus, the ''analyte -membrane'' association reactions cover the whole range of possible coordinative and ''weak'' interactions known in chemistry.…”

“…Originally, self assembled monolayers (SAMs) with charged head groups were used as electrode modifiers [4][5][6][7][8], but later the concept was extended to bio-membranes [9,10], artificial receptor molecules [11][12][13][14], LBlayers [12], peptides and proteins [15,16], and single stranded DNA or PNA [17,18]. Generally, all of these represent thin layers of less than one to a few nanometers thickness.…”

Resonance elastic light scattering (RELS) spectroscopy of fast non-Langmuirian ligand-exchange in glutathione-induced gold nanoparticle assembly

“…The interactions of adsorbed GSH with Cu 2+ have also been studied [31,32]. It has been shown that GSH-SAM's formed on Au piezoelectrodes can act as chemically controlled ion gates [30,[43][44][45][46] and as templates for metal depositions [31].…”

Electrochemical Studies of Derivatized Thiol Self-Assembled Monolayers on Gold Electrode in the Presence of Surfactants

“…An impedance method to evaluate the ionization of acidic and basic groups in surface confined monomolecular films was reported by Schweiss 16 and his colleagues. Takehara et al [17][18][19][20] carried out seriate studies by cyclic voltammetry (CV) on the permeation properties regulated by the solution pH value, lanthanide and alkaline earth metal ions on glutathione and cysteine-containing dipeptide monolayer modified gold electrode. However, the experimental techniques that they used were not the best choice.…”