An Observational Study to Evaluate the Prevalence of Erectile Dysfunction (ED) and Prescribing Pattern of Drugs in Patients with ED Visiting an Andrology Specialty Clinic, Mumbai: 2012-14

Mutha, Amit S.; Kulkarni, Vijay R.; Bhagat, Sagar; Beldar, Amit S.; Patel, Sadiq B

doi:10.7860/jcdr/2015/14520.6174

Cited by 6 publications

(5 citation statements)

References 22 publications

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“…Data showing PDE5is as the most commonly prescribed drugs for ED have been also reported in a study based on a drug utilization analysis on a cohort of patients attending the urology clinic from 2012 to 2014 (38); the authors reported that tadalafil emerged as the most commonly prescribed drug in 201 out of 606 cases (38). Similarly, Tsai et al (39) assessed changes in drug utilization over a decade from 1999 to 2011, reporting an increment in PDE5is sales of 5.9 folds, while the utilization of ICIs and penile implants remained stable.…”

Section: Pattern Of Drug Prescriptionmentioning

confidence: 73%

“…Several studies have comprehensively assessed the epidemiology of ED among populations with different characteristics, confirming the overall non-negligible prevalence of this disorder (1-5); however, only few surveys looked at the rate of and patterns of treatment of men seeking medical help for EF impairment (Tab. I) (34-42). Schouten et al (34), for instance, performed an interesting analysis aimed at describing the effect of the introduction of ED oral therapy in a cohort of 1643 men from 1994 to 2004, thus considering the introduction of PDE5Is more or less in the middle of the study.…”

Section: Pattern Of Drug Prescriptionmentioning

confidence: 99%

See 1 more Smart Citation

Medical Treatment of Erectile Dysfunction: Too Many Medical Prescriptions?

et al. 2017

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Erectile dysfunction (ED) is a worldwide commonly reported condition; epidemiological data showed a prevalence ranging from 2.3 to 53.4% within different population subsets. In this context, the advent of phosphodiesterase type 5 inhibitors (PDE5is) in the second mid of 1990s has deeply changed the treatment scenario of this bothersome condition. Being user-friendly compounds with an excellent overall safety profile, PDE5is emerged as the first-line treatment for ED, thus overcoming topical alprostadil and intracavernous injections (ICIs). However, available data on treatment-utilization patterns and medical prescriptions of PDE5is showed a range of as wide as 22-78% of patients reporting to purchase PDE5is even without a proper medical prescription. Moreover, an increase in the recreational use of PDE5is among young men has been observed in the last decades, with a worrisome diffusion of potential health-risky behaviours associated with this habit. Indeed, treatment of ED should carefully follow internationally based clinical guidelines to avoid inappropriate drug prescriptions, which may eventually expose treated patients to drug-related side effects. Thereof, a careful assessment of the so-called modifiable and reversible ED risk factors along with a patient-tailored screening for potential contraindications to the treatment itself should be performed in every case. Lastly, although conclusive data still lack, the potential association between life-risky PDE5is side effects (i.e. cardiovascular adverse events, melanoma skin cancer and worsening of prostate cancer outcomes) should be carefully taken into account when counselling patients for ED treatment.

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Section: Pattern Of Drug Prescriptionmentioning

confidence: 73%

Section: Pattern Of Drug Prescriptionmentioning

confidence: 99%

Medical Treatment of Erectile Dysfunction: Too Many Medical Prescriptions?

et al. 2017

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“…The IIEF demonstrates the sensitivity and specificity for detecting treatment-related changes in patients with erectile dysfunction [34] . International Index of Erectile Function (IIEF-15) Questionnaire were assessed through arbitrary score as No ED (≤25), mild ED (19)(20)(21)(22)(23)(24), mild to moderate ED (13)(14)(15)(16)(17)(18), moderate ED (7)(8)(9)(10)(11)(12) and severe ED (≥6) respectively. Since time immemorial, Unani medicine has been adopted by many cultures and is widely practiced all over the world.…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of erectile dysfunction in the Indian population is pegged merely at the global average (10 % of men <40, and up to 52 % of men > 40) [11] . Its incidence increases drastically from about 6% in the age group 20-29 years and 50-70% in the age group 40-79 years [12] . Age is a strong determinant of occurrence of ED, and epidemiological studies indicate a strong relationship between ED and advancing age [8] .…”

Section: Introductionmentioning

confidence: 97%

Efficacy of Dawa-ul-Khasak in treatment of erectile Dysfunction: An exploratory, single arm pre and post clinical trial

HM,

Siddiqui,

Quamri

et al. 2020

Pharma Innovation

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Background and Objectives: Erectile Dysfunction or Impotence is defined as inability to achieve or maintain an erection sufficient for satisfactory sexual performance. ED is well-defined under the heading of Zoaf-e-bah with the synonyms such as Nuqs-e-Nauoz, Zoaf-e-Inaaz, Isterqa-e-Qazeeb. Methods: 30 eligible patients of Erectile Dysfunction with IIEF-15 Score < 24 were enrolled in an open, single arm, pre and post, exploratory clinical trial with 4 weeks treatment duration. The test drug Dawaul-Khasak, with a dose of 7gms twice a day given. The effect of the study was assessed subjective and objectively in different follow ups. Patients were assessed for improvement in erectile function and sexual quality of life by using IIEF-15 Score and SQoL-M Scales respectively every 14 th and 28 th day of treatment. Patients were also assessed for subjective parameter on 7 th , 14 th , 21 st and 28 th day of study.

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“…ED is lately a common occurrence and its incidence is expected to increase significantly along with the increase in various lifestyle diseases. It constitutes an increasing obvious phenomenon during latest decades; the reasons of spreading of this phenomena lately even among younger men are obscure to explain [16]. As man grows older, sexual and non-sexual symptoms of testosterone deficiency can negatively affect the quality of life and cause considerable general health concerns but not in young age generations and not in such fast scenario [17].…”

Section: Discussionmentioning

confidence: 99%

Male Pelvic Congestion and Erectile Dysfunction Obscure Reasons for an Obvious Phenomenon among the Young

Nasrat¹,

Sayed²

2016

Gen Med

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The study aimed to demonstrate recent environmental reasons behind the rising phenomena of erectile dysfunction among young ages during late decades.Erectile dysfunction (ED) has got its impact on the quality of life of both partners. Erectile function (EF) is due to local arousal induced by release of nitric oxide. ED can be adequately prevented and improved by reduction of cardiovascular disease risk factors, regular exercise, weight loss and abstinence from smoking. An apparent role for cytokines in the pathophysiology of ED has been emerging; this substance can induce vascular spasm and affect vascular endothelial function including endothelial-derived nitric oxide production (NO). The association of male pelvic congestion with the frequency of male sexual dysfunction has been documented in literature. As concerns therapeutic modalities, medicines work essentially by mediating or enhancing the effect of NO. Colonic H. pylori strains were found frequently associated with pelvic congestion; H. pylori were considered as a possible underlying etiologic pathology in cases of pelvic pathology in general. The increased mucosal production of inflammatory cytokines of H. pylori could play an integral role in the pathogenesis of ED. The association of the colonic H. pylori strains with pelvic pathology, the role played by the inflammatory cytokines and the therapeutic effect of NO in ED were the scientific reasons to employ colon clear and blood-let out (BLO) cupping therapy in cases of ED. 40 patients with ED positive for colonic H. pylori strains were selected in two age groups; young and older age groups. They were scheduled for three sessions of colon clear, one each month, and a procedure BLO cupping therapy one week after the last colon clear. Marked improvement and most patients recovered their usual EF and sexual satisfaction. Employment of combined colon clear and cupping therapy in cases of ED is promising and is not just hypothetical.

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An Observational Study to Evaluate the Prevalence of Erectile Dysfunction (ED) and Prescribing Pattern of Drugs in Patients with ED Visiting an Andrology Specialty Clinic, Mumbai: 2012-14

Cited by 6 publications

References 22 publications

Medical Treatment of Erectile Dysfunction: Too Many Medical Prescriptions?

Medical Treatment of Erectile Dysfunction: Too Many Medical Prescriptions?

Efficacy of Dawa-ul-Khasak in treatment of erectile Dysfunction: An exploratory, single arm pre and post clinical trial

Male Pelvic Congestion and Erectile Dysfunction Obscure Reasons for an Obvious Phenomenon among the Young

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