An Ocular Surface Prosthesis for Keratoglobus and Terrien’s Marginal Degeneration

Mahadevan, Rajeswari; Fathima, Asra; Rajan, Rajni; Arumugam, Amudha Oli

doi:10.1097/opx.0000000000000200

Cited by 23 publications

(14 citation statements)

References 16 publications

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“…Conservative management in the form of spectacles and contact lenses is described though trivial trauma such as contact lens insertion and removal can cause rupture of the globe. [ 2 4 ] One of the 4 patients dispensed with PROSE developed hydrops, and we attribute this to the suction which is created when the lens is removed. [ 11 ] Though the fitting of the PROSE was optimal when dispensed after performing a 4 h challenge, the suction generated with daily lens removal might be responsible for the occurrence of hydrops over follow-up.…”

Section: Discussionmentioning

confidence: 99%

“…[ 2 ] Contact lenses are generally considered after balancing the risk of trauma. [ 2 4 ] Surgeries such as lamellar graft, epikeratoplasty, partial thickness corneoscleroplasty followed by smaller diameter penetrating keratoplasty (PK) are performed when necessary to improve the chances of survival of graft as well as to maintain the integrity of the globe. [ 3 5 6 7 ]…”

mentioning

confidence: 99%

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Keratoglobus: An experience at a tertiary eye care center in India

Rathi

Murthy

Bagga

et al. 2015

Indian J Ophthalmol

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Context:This study was carried out as a part of an internal audit and is the largest series of patients having keratoglobus, published in the literature. Poor visual acuity of the patients indicates the blinding nature of the disease.Aims:We report our experience with patients having keratoglobus at a tertiary eye care center in India.Settings and Design:Retrospective study.Materials and Methods:We analyzed adults and pediatric patients (<16 years) with keratoglobus, seen during 2008–2012. The age, gender, consanguinity, presenting ocular signs, ocular and systemic associations, visual acuity, corneal topography, and surgeries were documented.Results:Forty-eight patients (mean age 22 ± 15 years, 31 males) having keratoglobus were analyzed. 21 patients (42 eyes) were <16 years. Twelve eyes (16 events) had positive history of trauma. The presenting clinical signs were corneal scars/scars of tear repair (15 eyes), hydrops, healed and acute (14 eyes) and corneal or globe rupture (9 eyes). Best-corrected visual acuity was >20/40 in 6/42 (14.3%) pediatric eyes and 15/53 (28.30%) adults. Visual acuity ranging from counting of fingers to no light perception was noted in 20/53 (37.74%) adults and 21/42 (50%) pediatric patients; 13/20 (65%) with blue sclera and 8/22 eyes (36.37%) without blue sclera. Vernal keratoconjunctivitis was present in one pediatric patient. Choroidal osteoma, retinitis pigmentosa, and retinal detachment were present in adults. Surgeries performed were corneal tear repair (5 eyes), tissue adhesive application (2 eyes), descematopexy (4 eyes) and penetrating keratoplasty (PK - 8 eyes: Three had post-PK glaucoma, graft failure-one eye, 4 patients wore scleral lens - prosthetic replacement of the ocular surface ecosystem).Conclusions:About 50% of pediatric eyes (65% having blue sclera) had no functional vision. Trivial trauma was responsible for corneal rupture indicating need for protective glasses. About 50% patients had post-PK glaucoma though grafts were clear.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Keratoglobus: An experience at a tertiary eye care center in India

Rathi

Murthy

Bagga

et al. 2015

Indian J Ophthalmol

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“…Inflammation response associated with ScCL use has been reported with corneal infiltrates 35 and acute red eye due to poor compliance. 16 ScCL differs from other modalities because of their sealing effect and reduced tear exchange.…”

Section: Corneal Infiltrative Eventsmentioning

confidence: 99%

Scleral Lens Issues and Complications Related to Handling, Care and Compliance

Fadel

Toabe

2018

JCLRS

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Scleral contact lens (ScCL) handling may be challenging and is the principle reason for ScCL drop out. ScCL care systems are more intricate than other lens modalities and include solutions for cleaning, disinfection, storing, rinsing and filling the lens; respecting the use of each solution recommended is fundamental. Replacement of the lenses, solutions, case and plungers are important in order to decrease the risk of adverse events associated with ScCL wear. Compliance is crucial regarding hygiene, solution use, case and plunger care, wear time, follow-up schedule, and handling techniques. Non-compliance may lead to discontinuation of ScCL due to difficulties associated with this unique lens design. This paper presents complications secondary to handling, care and compliance that clinicians and patients may encounter while wearing ScCL. Instructions are provided to enhance the understanding on management surrounding these issues. This manuscript includes three tables to summarize types of complications, their symptoms, clinical signs, etiology, and management for a quick find index for easy consultation during daily clinical practice.

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“…Cotter and Rosenthal 69 Rosenthal et al 70 Rosenthal and Cotter 71 Rosenthal and Croteau 72 Jacobs and Rosenthal 73 Gungor et al 74 Lin et al 75 Lim et al 76 Grover et al 77 Gumus et al 78 Rathi et al 79 Baran et al 80 Cressey et al 81 Kalwerisky et al 82 Rathi et al 83,84 Dimit et al 85 Gire et al 86 Lee et al 87 Lim et al 88 Ling et al 89 Samimi et al 90 Arumugan et al 91 Ciralsky et al 92 Heur et al 93 Mahadevan et al 94 Rose K (Blanchard Contact Lens, Manchester, NH)…”

Section: Case Reports/retrospective Case Seriesmentioning

confidence: 99%

“…Romero-Rangel et al, 103 Schornack, 116 Pecego et al, 62 Lee et al, 87 Schornack 63 Congenital corneal hypoanesthesia Schein et al, 109 Gungor et al, 74 Alipour et al 105 Visual rehabilitation/corneal irregularity Primary corneal ectasia Foss et al, 102 Tan et al, 55,56 Pullum and Buckley, 57 Vreugdenhil et al, 117 Segal et al, 111 Rosenthal and Croteau, 72 Tomalla and Cagnolati, 54 Gungor et al, 74 Schornack and Patel, 60 Dalton and Sorbar, 64 Baran et al, 80 Pecego et al, 62 Lee et al, 87 Ortenberg et al, 100 Romero-Jiminez and Flores-Rodriguez, 118 Visser et al, 101 Arumugam et al, 91 Jagadeesh and Mahadevan, 119 Mahadevan et al 94 …”

Section: Corneal Dystrophy/ Degenerationmentioning

confidence: 99%