An open label clinical trial to evaluate the utility of a hydrolysed fish and rice starch elimination diet for the diagnosis of adverse food reactions in dogs

Matricoti, Irina; Noli, Chiara

doi:10.1111/vde.12680

Cited by 12 publications

(15 citation statements)

References 22 publications

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“…Surprisingly in this study, only one cat refused the diet, a percentage (3%) much lower than what has been described previously in dogs fed FUH and other hydrolysed diets. 16,23 Gastrointestinal signs associated with this diet were represented by vomiting and diarrhoea in three cases and just diarrhoea in a fourth one, for a total of 12.5% of cats, in line with a previous canine report in which constipation, soft faeces or diarrhoea were observed in 10% of dogs fed hydrolysed diets. 24 Cats not improving on the first ED trial were prescribed a second diet trial with a different hydrolysed protein and starch food, in order to minimise false negative diagnoses of AFR.…”

Section: Discussionsupporting

confidence: 89%

“…Similar to the canine study with the same product, this study suggests that FUH is suitable for use as an ED for the diagnosis of feline AFR. 16 A decrease of pruritus and clinical signs was observed in 17 of 25 (68%) cats that completed the ED, in line with what was observed in dogs. 16 However, only nine of 17 (53%) cats that improved on the ED and completed provocative challenges reacted to other foods.…”

Section: Discussionsupporting

confidence: 81%

“…A decrease of pruritus and clinical signs was observed in 17 of 25 (68%) cats that completed the ED, in line with what was observed in dogs. 16 However, only nine of 17 (53%) cats that improved on the ED and completed provocative challenges reacted to other foods. This resulted in an AFR prevalence of approximately 36% in cats with signs of cutaneous allergy (nine of 25 cats that completed the ED trial), similar to the percentage described in dogs, and higher than that reported previously in cats.…”

Section: Discussionmentioning

confidence: 99%

“…Similar to the canine study with the same product, this study suggests that FUH is suitable for use as an ED for the diagnosis of feline AFR. 16 …”

Section: Discussionmentioning

confidence: 99%

“…14 , 15 Recently, a hydrolysed fish protein (herring) and rice starch diet (Vet Life Canine UltraHypo, Farmina Pet Food; Nola, NA, Italy) claiming the absence of peptides >6 kDa in size, was considered suitable for the diagnosis of AFR in dogs. 16 A feline formulation of the same diet is commercially available. The aim of this study was to evaluate the performance of Vet Life Feline UltraHypo (FUH) diet for the diagnosis of AFR in cats with nonseasonal pruritic dermatitis.…”

Section: Introductionmentioning

confidence: 99%

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The usefulness of a hydrolysed fish and rice starch elimination diet for the diagnosis of adverse food reactions in cats: an open clinical trial

Noli¹,

Beltrando

2021

Veterinary Dermatology

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Background -Diagnosis of adverse food reaction (AFR) is based on an eight week elimination diet (ED) and is confirmed by relapse upon re-challenge with the previously fed diet. Hydrolysed EDs are commonly used for this purpose.Objective -To evaluate the commercially available hydrolysed fish protein and rice starch ED Farmina UltraHypo (FUH) for the diagnosis of feline AFR.Animals -Thirty-two nonseasonally pruritic cats.Methods and materials -Pruritus was assessed with a new dual Visual Analog Scale, lesions with the Scoring Feline Allergic Dermatitis scale and Quality of Life with a validated questionnaire on days 0 and 56. Short-acting corticosteroids or oclacitinib were permitted during the first six weeks. Cats showing 50% pruritus and/or lesional improvement were separately challenged with their prior diet, fish and rice. Cats not responding to the study diet were fed another hydrolysed diet for two months.Results -Twenty-five cats completed the ED: four dropped out due to vomiting and/or diarrhoea, one owing to low palatability and two were lost to follow-up. In 17 cats, pruritus improved by >50% and these underwent dietary challenges. Of these, nine reacted to their prior diet and/or fish and/or rice and were diagnosed with AFR, while eight did not relapse (and a diagnosis of AFR was considered to be doubtful). Of the eight cats in which pruritus did not improve, four underwent a second ED with no improvement.Conclusion and clinical importance -FUH may be a useful ED for the diagnosis of feline AFR, even in cats reacting to fish or rice.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 99%

“…Similar to the canine study with the same product, this study suggests that FUH is suitable for use as an ED for the diagnosis of feline AFR. 16 …”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%