An open-source handheld spectrometer for colorimetric and fluorescence analyses

Yu, Zhi-Cheng; Meng, Ruidong; Deng, Suqi; Li, Jia

doi:10.1016/j.saa.2022.122072

Cited by 5 publications

(3 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A calibration plot was drawn to determine the unknown concentration of As 3+ based on the observed color change. Yu and team 79 developed a cost-effective, wireless, and handheld spectrophotometer designed for the colorimetric analysis of DNA, BSA, and Cu 2+ metal ions. They assembled various components using 3D printing technology.…”

Section: Handheld Colorimetry Devicesmentioning

confidence: 99%

Progress in the design of portable colorimetric chemical sensing devices

Kant,

Shrivas,

Tejwani

et al. 2023

Nanoscale

View full text Add to dashboard Cite

show abstract

Section: Handheld Colorimetry Devicesmentioning

confidence: 99%

Progress in the design of portable colorimetric chemical sensing devices

Kant,

Shrivas,

Tejwani

et al. 2023

Nanoscale

View full text Add to dashboard Cite

show abstract

“…Furthermore, the required instrumentation employed for fluorometric measurements has evolved in recent years from static designs mainly focused on laboratory assays towards more flexible, portable and handheld devices [10][11][12][13][14][15][16], which can be easily operated for in situ experiments. Thus, the increasing availability of the necessary components to build fluorometric detection devices, such as intense light sources with different excitation wavelengths (LEDs, fiber optic) [17,18] and compact micro-spectrometers for light analysis (C1280 MA) [19], and the existence of numerous computer-programmable microcontrollers (Raspberry Pi, Arduino) [20][21][22][23] allow the building of low-cost equipment [24][25][26] with unique features for in situ sample analysis with spectrofluorometric detection.…”

Section: Introductionmentioning

confidence: 99%

Design of a Portable and Reliable Fluorimeter with High Sensitivity for Molecule Trace Analysis

et al. 2023

View full text Add to dashboard Cite

There is a growing need for portable, highly sensitive measuring equipment to analyze samples in situ and in real time. For these reasons, it is becoming increasingly important to research new experimental equipment to carry out this work with advanced, robust and low-cost devices. In this framework, a flexible, portable and low-cost fluorimeter (under EUR 500), based on a C12880 MA MEMS micro-spectrometer with an Arduino compatible breakout board, has been developed for the trace analysis of biological substances. The proposed system can employ two selectable excitation sources for flexibility, one in the visible region at 405 nm (incorporated in the board) and an external LED at 365 nm in the UV region. This additional excitation source can be easily interchanged, varying the LED type for investigating any fluorophore compound of interest. The measurement process is micro-controlled, which allows the precise control of the spectrometer sensitivity by adjusting the integration time of each experiment separately. Data acquisition is easy, reliable and interfaced with a spreadsheet for fast spectra visualization and calculations. For testing the performance of the new device in fluorescence measurements, different fluorophore molecules which can be commonly found in biological samples, such as Fluorescein, Riboflavin, Quinine, Rhodamine b and Ru (II)-bipyridyl, have been employed. A high sensitivity and low quantitation limits (in the ppb range) have been found in all cases for the investigated chemicals. The portable device is also suitable for the study of other interesting phenomena, such as fluorescence quenching induced by chemical agents (such as halide anions or even auto-quenching). In this sense, an application for the quantification of chloride anions in aqueous solutions has been performed obtaining a LOD value of 18 ppm. The obtained results for all chemicals investigated with the proposed fluorimeter are always very similar in quantification figures, or even better than the data reported in literature, when using commercial laboratory equipment.

show abstract

“…5,6 By incorporating various sensors such as optical sensors, 2,7,8 electrochemical sensors, 9 and biosensors, 3,10 these devices exhibit exceptional sensitivity and selectivity, and are particularly valuable for food quality control and other applications. 2 Optical sensors, for instance, exploit the interaction of light with substances to measure parameters like reflectance, 7,8 fluorescence, 11 absorbance 11,12 or chemiluminescence. 13 The synergy between the DIY movement and IoT fosters innovation through accessible materials, open-source projects, and knowledge sharing, democratizing access to analytical chemistry and propelling advancements in substance analysis.…”

Section: Introductionmentioning

confidence: 99%