2006
DOI: 10.1111/j.0924-2708.2006.00113.x
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An open trial of Omega-3 fatty acids for depression in pregnancy

Abstract: This open trial provides data to support the need for randomized controlled dose-finding trials of omega-3 fatty acids in major depressive episodes during pregnancy.

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Cited by 39 publications
(27 citation statements)
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“…However, there are only few intervention trials designed to specifically address this endpoint. Two recent small trials on v-3 FA intake of up to 2.8 g/day showed a significant reduction in depression during pregnancy and the postpartum period [35,36]. In these studies, v-3 FA appeared beneficial and improved depressive symptoms.…”
Section: Effects On Maternal and Pregnancy Outcomesmentioning
confidence: 90%
“…However, there are only few intervention trials designed to specifically address this endpoint. Two recent small trials on v-3 FA intake of up to 2.8 g/day showed a significant reduction in depression during pregnancy and the postpartum period [35,36]. In these studies, v-3 FA appeared beneficial and improved depressive symptoms.…”
Section: Effects On Maternal and Pregnancy Outcomesmentioning
confidence: 90%
“…This is further supported by the findings that n-3 PUFAs are effective in the treatment of bipolar depression [26,31] , but the result was inconsistent [36] . n-3 PUFA monotherapy has been used for pregnant women because it is thought to be safe and necessary for optimal development in the fetal brain [37] . The use of n-3 PUFA monotherapy for pregnant women with depression has recently been supported by our 8-week, double-blind, placebo-controlled study, revealing that subjects treated with n-3 PUFAs had significant lower scores on the Hamilton Depression Rating Scale, a higher response rate, and a higher remission rate at the end of the study [32] .…”
Section: Role Of N-3 Pufas In Depressionmentioning
confidence: 99%
“…The first study (87) has used an EPA and DHA combination for the treatment of depression in 15 women during the pregnancy. The decrease rate, according to the Edinburgh Postnatal Depression Scale, was 40.9%.…”
Section: V-3 and Major Depressionmentioning
confidence: 99%