An Operated Case of Hyperparathyroidism Relating to Administration of Lithium Carbonate

Takami, Hiroshi; Sekine, Masaru; Koudaira, Hiroto; Otsuka, Miyuki; Hasumi, Tadahiko; Hanatani, Yuji; Asagoe, Tatsuo; Kodaira, Susumu

doi:10.3919/ringe1963.53.2917

The journal of the Japanese Practical Surgeon Society

1992

DOI: 10.3919/ringe1963.53.2917

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An Operated Case of Hyperparathyroidism Relating to Administration of Lithium Carbonate

Hiroshi Takami

Masaru Sekine

Hiroto Koudaira

et al.

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1995

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“…Their incidences in patients taking lithium carbonate are said to be relatively higher than expected at 10-40% [1][2][3]. In Japan, on the other hand, only one case of the disease has been reported by Takami et al [4] and there were no patients with a history of lithium administration among 145 patients treated surgically due to primary hyperparathyroidism at Shinshu University Hospital, Matsumoto, Japan in the 20 years from January, 1974 to December, 1993. In view of this, we investigated the serum calcium level and parathyroid function to find out whether hypercalcemia and hyperparathyroidism are rare or not patients taking lithium carbonate in Japan.…”

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confidence: 93%

Effect of Lithium on Serum Calcium Level and Parathyroid Function in Manic-Depressive Patients.

et al. 1995

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Abstract. The purpose of this study is to find out whether hypercalcemia and hyperparathyroidism are rare or not in manic-depressive patients taking lithium carbonate. The subjects were 13 patients receiving lithium and 19 healthy subjects not receiving it as normal controls. Serum ionized calcium (Ca), serum parathyroid hormone (PTH), urinary calcium and cyclic AMP (CAMP) were measured. Cervical ultrasonographic examination was also performed. The mean serum Ca++ level in the lithium administered group was significantly higher than that in the control group (P<0.02). There was no significant difference between the serum PTH levels in the two groups. The mean urinary calcium level in the lithium administered group was below the normal range, but the mean urinary cAMP level was within the normal range. Although a parathyroid cyst was found in one lithium administered patient on ultrasonographic examination, no swelling of the parathyroid gland was observed in the other patients in the lithium administered group or in any of the control subjects. In the present study, no distinct hyperparathyroidism was found in the patients in the lithium administered group. Lithium administration affects calcium metabolism in manic-depressive patients and hypercalcemia seems to be one of the complications needing attention at the time of lithium administration.

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Effect of Lithium on Serum Calcium Level and Parathyroid Function in Manic-Depressive Patients.

et al. 1995

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An Operated Case of Hyperparathyroidism Relating to Administration of Lithium Carbonate

Cited by 1 publication

References 10 publications

Effect of Lithium on Serum Calcium Level and Parathyroid Function in Manic-Depressive Patients.

Effect of Lithium on Serum Calcium Level and Parathyroid Function in Manic-Depressive Patients.

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