An Optical Chiral Sensor Based on Weak Measurement for the Real-Time Monitoring of Sucrose Hydrolysis

Abstract

A chiral sensor with optical rotation detection based on weak measurement for the kinetic study of sucrose hydrolysis is presented. Based on the polarization modulation to the pre-selection state, the optical rotation of chiral sample was accurately determined through the central wavelength shift of the output spectrum. With this approach, the concentration response curves of sucrose and its hydrolysis products, i.e., fructose and glucose, were experimentally obtained for the hydrolysis analysis. By collecting the output spectrum with a frequency of 100 Hz and fitting the central wavelength shift synchronously during the measurement, the sucrose hydrolysis process was monitored in real time. Different hydrolysis conditions with varied concentration of invertase enzyme and citrate were implemented in this work. As a consequence, the real-time hydrolysis curves of the hydrolysis process with distinct velocities was achieved and analyzed. Such a kinetic monitoring about sucrose hydrolysis with optical rotation detection technology played a critical role in the researches involving sucrose, and also revealed the great potential of weak measurement in intersections, such as food safety inspection and chemical analysis.

Fabrication of Efficient and Non-Enzymatic Electrochemical Sensors for the Detection of Sucrose

“…The most widely used sweetener, sucrose, is not only extracted mostly from sugarcane but also from fruits and vegetables. Up to 99.5% of final prepared white sugar is sucrose, which is the most crucial component in the synthesis of sugar [ 1 , 2 ]. Animals consume sucrose to maintain their energy levels, which affects their lipid metabolism and insulin effectiveness [ 3 , 4 ].…”

Molecular Level Sucrose Quantification: A Critical Review

“…Recently, Li et al [ 29 ] reported a polarimetric method to measure sucrose inversion, in real-time, at concentrations range of M. Instead of sodium D light, Li et al used pulses of polarized light with a Gaussian distribution centered at 830 nm and amplitude of 10 nm, generated by a super luminescent diode (SLD) with a Gaussian filter. The reaction of sucrose with INV decreases the optical activity in the solution, changing the photon’s polarization at the optical interface and displacing the Gaussian center distribution of the photon wavelengths [ 29 ]. This is known as the photonic spin Hall effect due to the spin–orbit coupling in polarized photons.…”

“…This is known as the photonic spin Hall effect due to the spin–orbit coupling in polarized photons. This spin–orbit coupling is a weak interaction that the authors managed to amplify under the approximation of quantum weak measurement, achieving the detection of sucrose in a linear range from 2.28 M to 50.2 mM [ 29 , 30 ].…”

Oxidation Analysis of l-Cysteine with a Chiral Sensor Based on Quantum Weak Measurement

“…34 Furthermore, they also utilized quantum weak measurement to monitor the real-time hydrolysis process of sucrose in 2021. 35 The optical rotation sensor has the capability to detect amino acids and proteins. 36 Some previous studies on glucose or chiral optical sensors based on weak measurement have demonstrated encouraging outcomes.…”

“…In 2016, a research group at Tsinghua University applied quantum weak measurement to detect glucose concentration . Furthermore, they also utilized quantum weak measurement to monitor the real-time hydrolysis process of sucrose in 2021 . The optical rotation sensor has the capability to detect amino acids and proteins .…”